Inflammation is increasingly recognized as being of both physiological and pathological
importance in the immature brain. The rationale of this review is to present an update on this …

Hyperglycemia, a commonly exhibited metabolic disorder in critically ill patients, activates
the body's inflammatory defense mechanism, causing the waterfall release of numerous …

Histone deacetylases (HDACs) regulate inflammatory gene expression, as indicated by the
potent antiinflammatory activity of pan-HDAC inhibitors. However, the specific contribution of …

DNA methylation of retroviral promoters and enhancers localized in the provirus 5′ long
terminal repeat (LTR) is considered to be a mechanism of transcriptional suppression that …

Mycotoxin-induced liver injury is often accompanied by oxidative stress (OS) and
inflammation. This research aimed to explore the potential mechanism of sodium butyrate …

Inflammatory bowel disease (IBD) refers to a group of heterogeneous disorders associated
with chronic inflammation of the gut, having a high rate of incidence in the world. In the …

Poly (ADP-ribose) polymerase-1 (PARP-1) and nuclear factor κB (NF-κB) have both been
demonstrated to play a pathophysiological role in a number of inflammatory disorders. We …

Background and purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease.
Histone deacetylase inhibitors (HDACi), a new class of anti‐cancer agents, have recently …

Cytokines such as interferons (IFNs) activate signal transducers and activators of
transcription (STATs) via phosphorylation. Histone deacetylases (HDACs) and the histone …

Valproic acid (VPA), a widely prescribed drug for seizures and bipolar disorder, has been
shown to be an inhibitor of histone deacetylase (HDAC). Our previous study has …