Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Exercise mimetics are a proposed class of therapeutics that specifically mimic or enhance
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …

Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Childhood obesity is characterized by an increased risk of several metabolic derangements
including insulin resistance (IR). The strongest recommendations to prevent obesity and …

Regular physical exercise has been recognized as a potent modulator of immune function,
with its effects including enhanced immune surveillance, reduced inflammation, and …

Despite advances in treatments and therapies, cardiovascular diseases (CVDs) remain one
of the leading causes of death worldwide. The discovery that most of the human genome …

Physical exercise is established as an important factor of health and generally is
recommended for its positive effects on several tissues, organs, and systems. These positive …

Exercise intolerance remains a major unmet medical need in patients with heart failure (HF).
Skeletal myopathy is currently considered as the major limiting factor for exercise capacity in …

In modern societies, ageing and obesity represent medical challenges for healthcare
professionals and caregivers. Obesity and ageing share common features including the …

Lifestyle modification represents the first‐line strategy for the prevention and treatment of
type 2 diabetes mellitus (T2DM), which is frequently associated with obesity and …