[HTML][HTML] Cancer cells change their glucose metabolism to overcome increased ROS: One step from cancer cell to cancer stem cell?

ZG Movahed, M Rastegari-Pouyani… - Biomedicine & …, 2019 - Elsevier
Cancer cells can adapt to low energy sources in the face of ATP depletion as well as to their
high levels of ROS by altering their metabolism and energy production networks which might …

Covalent inhibitors of GAPDH: From unspecific warheads to selective compounds

A Galbiati, A Zana, P Conti - European Journal of Medicinal Chemistry, 2020 - Elsevier
Targeting glycolysis is an attractive approach for the treatment of a wide range of
pathologies, such as various tumors and parasitic infections. Due to its pivotal role in the …

Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells

NM Grüning, M Rinnerthaler, K Bluemlein, M Mülleder… - Cell metabolism, 2011 - cell.com
In proliferating cells, a transition from aerobic to anaerobic metabolism is known as the
Warburg effect, whose reversal inhibits cancer cell proliferation. Studying its regulator …

Proteomic analysis of Burkholderia zhejiangensis CEIB S4–3 during the methyl parathion degradation process

ML Castrejón-Godínez, E Tovar-Sánchez… - Pesticide Biochemistry …, 2022 - Elsevier
Methyl parathion is an organophosphorus pesticide widely employed worldwide to control
pests in agricultural and domestic environments. However, due to its intensive use, high …

Mechanism of GAPDH Redox Signaling by H2O2 Activation of a Two−Cysteine Switch

PA Hyslop, MO Chaney - International Journal of Molecular Sciences, 2022 - mdpi.com
Oxidation of glyceraldehyde− 3− phosphate dehydrogenase (GAPDH) by reactive oxygen
species such as H2O2 activate pleiotropic signaling pathways is associated with …

Glutathione is essential to preserve nuclear function and cell survival under oxidative stress

E Hatem, V Berthonaud, M Dardalhon, G Lagniel… - Free Radical Biology …, 2014 - Elsevier
Glutathione (GSH) is considered the most important redox buffer of the cell. To better
characterize its essential function during oxidative stress conditions, we studied the …

H2O2 delivery to cells: steady-state versus bolus addition

HS Marinho, L Cyrne, E Cadenas, F Antunes - Methods in Enzymology, 2013 - Elsevier
Abstract Hydrogen peroxide (H 2 O 2) is a ubiquitous biological molecule whose wide range
of biological functions depends on its concentration. In this chapter, we compare the delivery …

Soft cysteine signaling network: the functional significance of cysteine in protein function and the soft acids/bases thiol chemistry that facilitates cysteine modification

RS Wible, TR Sutter - Chemical Research in Toxicology, 2017 - ACS Publications
The unique biophysical and electronic properties of cysteine make this molecule one of the
most biologically critical amino acids in the proteome. The defining sulfur atom in cysteine is …

Preservation of non‐Saccharomyces yeasts: Current technologies and challenges

L Casas‐Godoy, M Arellano‐Plaza… - … reviews in food …, 2021 - Wiley Online Library
There is a recent and growing interest in the study and application of non‐Saccharomyces
yeasts, mainly in fermented foods. Numerous publications and patents show the importance …

Free Radical Scavenging Activity of 4-(3,4-Dihydroxybenzoyloxymethyl)phenyl-O-β-d-glucopyranoside from Origanum vulgare and Its Protection against Oxidative …

CH Liang, LP Chan, HY Ding, EC So… - Journal of agricultural …, 2012 - ACS Publications
4-(3, 4-Dihydroxybenzoyloxymethyl) phenyl-O-β-d-glucopyranoside (DBPG), a polyphenolic
glycoside, isolated from Origanum vulgare has shown 1, 1-diphenyl-2-picrylhydrazyl …