Reconstruction of bone defects, especially the critical-sized defects, with mechanical
integrity to the skeleton is important for a patient's rehabilitation, however, it still remains …

Organs are complex systems composed of different cells, proteins and signalling molecules
that are arranged in a highly ordered structure to orchestrate a myriad of functions in our …

Thermoresponsive polymers hold great potential in the biomedical field, since they enable
the fabrication of cell sheets, in situ drug delivery and 3D-printing under physiological …

Over the last decades, the fabrication of 3D tissues has become commonplace in tissue
engineering and regenerative medicine. However, conventional 3D biofabrication …

Biofabrication holds the potential to generate constructs that more closely recapitulate the
complexity and heterogeneity of tissues and organs than do currently available regenerative …

Methods for depositing thin films are important in generating functional materials for diverse
applications in a wide variety of fields. Over the last half-century, the layer-by-layer assembly …

The drastic development of polymeric materials for a wide range of biomedical and
biomaterial applications has been explored in the last few decades. Among these materials …

Cell-based scaffold-free therapies seek to develop in vitro organotypic three-dimensional
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …

Thorough understanding of how to control cell behaviors including cell adhesion,
orientation, migration and differentiation on an artificial surface is critical in materials and life …

New manufacturing technologies under the banner of rapid prototyping enable the
fabrication of structures close in architecture to biological tissue. In their simplest form, these …