A horse's success on the racetrack is determined by genetics, training and nutrition, and
their translation into physical traits such as speed, endurance and muscle strength …

Skeletal muscles in horses are characterised by specific adaptations, which are the result of
the natural evolution of the horse as a grazing animal, centuries of selective breeding and …

Background A comprehensive analysis of gene expression profiling across tissues can
provide necessary information for an in-depth understanding of their biological functions. We …

Athletic performance is influenced by a complex interplay among the environment and a
suite of genes, which contributes to system‐wide structure and function. In a panel of elite …

Exercise benefits M2 macrophage polarization, energy homeostasis and protects against
obesity partially through exercise-induced circulating factors. Here, by unbiased quantitative …

The athletic horse, despite being over 50% muscle mass, remains understudied with regard
to the effects of exercise and training on skeletal muscle metabolism. To begin to address …

Reasons for performing study: The wild progenitors of the domestic horse were subject to
natural selection for speed and stamina for millennia. Uniquely, this process has been …

Background Within the animal kingdom, horses are among the most powerful aerobic
athletic mammals. Determination of muscle respiratory capacity and control improves our …

Key points Muscle mitochondrial networks changed from a longitudinal, fibre parallel
orientation to a perpendicular configuration during postnatal development. Mitochondrial …

Background Selection for exercise-adapted phenotypes in the Thoroughbred racehorse has
provided a valuable model system to understand molecular responses to exercise in …