The immunological and metabolic landscape in primary and metastatic liver cancer

X Li, P Ramadori, D Pfister, M Seehawer… - Nature Reviews …, 2021 - nature.com
The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …

ICAM-1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis

TM Bui, HL Wiesolek, R Sumagin - Journal of Leucocyte Biology, 2020 - academic.oup.com
ICAM-1 is a cell surface glycoprotein and an adhesion receptor that is best known for
regulating leukocyte recruitment from circulation to sites of inflammation. However, in …

ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disorders

V Singh, R Kaur, P Kumari, C Pasricha, R Singh - Clinica Chimica Acta, 2023 - Elsevier
Leukocyte migration from the vascular compartment is critical for normal lymphocyte
recirculation in specific tissues and immune response in inflammatory locations. Leukocyte …

The role of sinusoidal endothelial cells in the axis of inflammation and cancer within the liver

AL Wilkinson, M Qurashi, S Shetty - Frontiers in physiology, 2020 - frontiersin.org
Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

Emerging CAR-T cell therapy for the treatment of triple-negative breast cancer

S Dees, R Ganesan, S Singh, IS Grewal - Molecular cancer therapeutics, 2020 - AACR
Triple-negative breast cancer (TNBC), a highly aggressive breast cancer subtype that lacks
estrogen receptor, progesterone receptor, and HER2 expression, does not respond to …

[HTML][HTML] Firefighters' occupational exposure: Contribution from biomarkers of effect to assess health risks

B Barros, M Oliveira, S Morais - Environment international, 2021 - Elsevier
Firefighting is physically and physiologically exhausting besides encompassing exposure to
toxic fire emissions. Biomonitoring studies from the past five years have been significantly …

Cannabis: a multifaceted plant with endless potentials

E Fordjour, CF Manful, AA Sey, R Javed… - Frontiers in …, 2023 - frontiersin.org
Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses in
medicine, agriculture, food, and cosmetics. This review attempts to evaluate the available …

Gene regulation of intracellular adhesion molecule-1 (ICAM-1): A molecule with multiple functions

M Singh, M Thakur, M Mishra, M Yadav, R Vibhuti… - Immunology letters, 2021 - Elsevier
Abstract Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied
inducible cell adhesion molecules which is responsible for several immune functions like T …

ICAM-1 promotes cancer progression by regulating SRC activity as an adapter protein in colorectal cancer

EJ Lim, JH Kang, YJ Kim, S Kim, SJ Lee - Cell death & disease, 2022 - nature.com
Colorectal cancer (CRC) has a 5-year survival rate of< 10%, as it can metastasize to the
lungs and liver. Anticancer drugs and targeted therapies used to treat metastatic colorectal …

[HTML][HTML] Antitumor effects of curcumin on the proliferation, migration and apoptosis of human colorectal carcinoma HCT‑116 cells

L Xiang, B He, Q Liu, D Hu, W Liao, R Li… - Oncology …, 2020 - spandidos-publications.com
Curcumin is the main component of the Chinese herbal plant turmeric, which has been
demonstrated to possess antitumor and other pharmacological properties. The aim of the …