The role of therapeutic drug monitoring in the management of patients with human immunodeficiency virus infection
E Pretorius, H Klinker… - Therapeutic drug …, 2011 - journals.lww.com
Therapeutic drug monitoring (TDM) is a well-established method to optimize dosing
regimens in individual patients for drugs that are characterized by a narrow therapeutic …
regimens in individual patients for drugs that are characterized by a narrow therapeutic …
Validation of a rapid and sensitive high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) assay for the simultaneous determination of …
L Else, V Watson, J Tjia, A Hughes, M Siccardi… - … of Chromatography B, 2010 - Elsevier
Clinical pharmacokinetic studies of antiretrovirals require accurate and precise
measurement of plasma drug concentrations. Here we describe a simple, fast and sensitive …
measurement of plasma drug concentrations. Here we describe a simple, fast and sensitive …
A LC–tandem MS assay for the simultaneous measurement of new antiretroviral agents: Raltegravir, maraviroc, darunavir, and etravirine
A Fayet, A Béguin, B Zanolari, S Cruchon… - … of Chromatography B, 2009 - Elsevier
Raltegravir (RAL), maraviroc (MVC), darunavir (DRV), and etravirine (ETV) are new
antiretroviral agents with significant potential for drug interactions. This work describes a …
antiretroviral agents with significant potential for drug interactions. This work describes a …
Saquinavir, the pioneer antiretroviral protease inhibitor
CJL la Porte - Expert opinion on drug metabolism & toxicology, 2009 - Taylor & Francis
Background: The treatment of HIV infection underwent a major change in 1995 when
saquinavir was the first protease inhibitor introduced into the market. This drug made the use …
saquinavir was the first protease inhibitor introduced into the market. This drug made the use …
Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography–triple quadrupole mass …
R Ter Heine, H Rosing, ECM Van Gorp… - … of Chromatography B, 2008 - Elsevier
A bioanalytical method for the determination of most commonly prescribed protease
inhibitors (atazanavir, darunavir, lopinavir and ritonavir) and non-nucleoside reverse …
inhibitors (atazanavir, darunavir, lopinavir and ritonavir) and non-nucleoside reverse …
An HPLC-PDA method for the simultaneous quantification of the HIV integrase inhibitor raltegravir, the new nonnucleoside reverse transcriptase inhibitor etravirine …
A D'Avolio, L Baietto, M Siccardi… - Therapeutic Drug …, 2008 - journals.lww.com
A new method using high-performance liquid chromatography coupled with photo diode
array detection was developed and validated for the quantification of plasma concentrations …
array detection was developed and validated for the quantification of plasma concentrations …
Validation of a fast method for quantitative analysis of elvitegravir, raltegravir, maraviroc, etravirine, tenofovir, boceprevir and 10 other antiretroviral agents in human …
Z Djerada, C Feliu, C Tournois, D Vautier… - … of Pharmaceutical and …, 2013 - Elsevier
Therapeutic drug monitoring (TDM) of antiretrovirals requires accurate and precise analysis
of plasma drug concentrations. This work describes a simple, fast and sensitive UPLC …
of plasma drug concentrations. This work describes a simple, fast and sensitive UPLC …
HPLC–MS method for the simultaneous quantification of the antileukemia drugs imatinib, dasatinib and nilotinib in human peripheral blood mononuclear cell (PBMC)
A D'Avolio, M Simiele, S De Francia, A Ariaudo… - … of pharmaceutical and …, 2012 - Elsevier
A new method using high performance liquid chromatography coupled with electrospray
mass spectrometry is described for the quantification of PBMC concentration of tyrosine …
mass spectrometry is described for the quantification of PBMC concentration of tyrosine …
Rapid, simultaneous determination of lopinavir and ritonavir in human plasma by stacking protein precipitations and salting-out assisted liquid/liquid extraction, and …
F Myasein, E Kim, J Zhang, H Wu… - Analytica Chimica Acta, 2009 - Elsevier
Lopinavir and ritonavir are co-formulated in Kaletra® approved for the treatment of human
immunodeficiency virus infection. A validated analytical method is mandatory for clinical …
immunodeficiency virus infection. A validated analytical method is mandatory for clinical …
Cerebrospinal fluid inhibitory quotients of antiretroviral drugs in HIV-infected patients are associated with compartmental viral control
A Calcagno, M Simiele, MC Alberione… - Clinical Infectious …, 2015 - academic.oup.com
Antiretroviral concentrations in cerebrospinal fluid (CSF) are variable; darunavir and
efavirenz show levels several times higher than HIV-1 95% inhibitory concentrations (IQ95) …
efavirenz show levels several times higher than HIV-1 95% inhibitory concentrations (IQ95) …