Machine learning in medical applications: A review of state-of-the-art methods

M Shehab, L Abualigah, Q Shambour… - Computers in Biology …, 2022 - Elsevier
Applications of machine learning (ML) methods have been used extensively to solve various
complex challenges in recent years in various application areas, such as medical, financial …

Fluid transport in the brain

MK Rasmussen, H Mestre… - Physiological …, 2022 - journals.physiology.org
The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

The human cell count and size distribution

IA Hatton, ED Galbraith, NSC Merleau… - Proceedings of the …, 2023 - National Acad Sciences
Cell size and cell count are adaptively regulated and intimately linked to growth and
function. Yet, despite their widespread relevance, the relation between cell size and count …

[HTML][HTML] A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

Z Yao, CTJ Van Velthoven, TN Nguyen, J Goldy… - Cell, 2021 - cell.com
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …

[HTML][HTML] Neuroinfection may contribute to pathophysiology and clinical manifestations of COVID‐19

L Steardo, L Steardo Jr, R Zorec… - Acta Physiologica …, 2020 - ncbi.nlm.nih.gov
The new coronavirus, classified as severe acute respiratory syndrome (SARS)-CoV-2 that
emerged in Hubei province in China, causes a new coronavirus disease, which was termed …

Conserved cell types with divergent features in human versus mouse cortex

RD Hodge, TE Bakken, JA Miller, KA Smith, ER Barkan… - Nature, 2019 - nature.com
Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA …

Human brain organogenesis: Toward a cellular understanding of development and disease

KW Kelley, SP Pașca - Cell, 2022 - cell.com
The construction of the human nervous system is a distinctly complex although highly
regulated process. Human tissue inaccessibility has impeded a molecular understanding of …

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

JJ Lee, R Wedow, A Okbay, E Kong, O Maghzian… - Nature …, 2018 - nature.com
Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …

Application of graph theory for identifying connectivity patterns in human brain networks: a systematic review

FV Farahani, W Karwowski, NR Lighthall - frontiers in Neuroscience, 2019 - frontiersin.org
Background: Analysis of the human connectome using functional magnetic resonance
imaging (fMRI) started in the mid-1990s and attracted increasing attention in attempts to …

Beyond the GFAP-astrocyte protein markers in the brain

AM Jurga, M Paleczna, J Kadluczka, KZ Kuter - Biomolecules, 2021 - mdpi.com
The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …