Monozygotic (MZ) twins and higher-order multiples arise when a zygote splits during pre- implantation stages of development. The mechanisms underpinning this event have …
A Varjonen, C Schwarz, E Vuoksimaa - Cerebral Cortex, 2023 - academic.oup.com
Twin samples allow to conduct a quasi-experimental co-twin case–control approach that can control for genetic and environmental confounding in brain–cognition associations, being …
BW van der Kolk, S Saari, A Lovric, M Arif… - Cell Reports …, 2021 - cell.com
Tissue-specific mechanisms prompting obesity-related development complications in humans remain unclear. We apply multiomics analyses of subcutaneous adipose tissue and …
S Lundgren, S Kuitunen, KH Pietiläinen… - Journal of Internal …, 2022 - Wiley Online Library
Background Obesity is a heritable complex phenotype that can increase the risk of age‐ related outcomes. Biological age can be estimated from DNA methylation (DNAm) using …
J Ahlberg, M Piirtola, F Lobbezoo… - Journal of Oral …, 2020 - Wiley Online Library
Background Sleep bruxism (SB) and awake bruxism (AB) have been considered different entities, although co‐occurrence between them has been shown. While genetic factors have …
Purpose Greater leisure-time physical activity (LTPA) associates with healthier lives, but knowledge regarding occupational physical activity (OPA) is more inconsistent. DNA …
H Mbarek, SD Gordon, DL Duffy, N Hubers… - Human …, 2024 - academic.oup.com
STUDY QUESTION Which genetic factors regulate female propensity for giving birth to spontaneous dizygotic (DZ) twins? SUMMARY ANSWER We identified four new loci …
Background Sarcopenia, characterised by an accelerated loss of skeletal muscle mass and function, is associated with negative outcomes. This study aimed to evaluate factors …
T Föhr, A Hendrix, A Kankaanpää… - International Journal of …, 2024 - nature.com
Abstract Background Metabolic syndrome (MetS) is associated with premature aging, but whether this association is driven by genetic or lifestyle factors remains unclear. Methods …