Endothelin (ET) peptides and their receptors are intimately involved in the physiological
control of systemic blood pressure and body Na homeostasis, exerting these effects through …

The kidney plays a fundamental role in maintaining body salt and fluid balance and blood
pressure homeostasis through the actions of its proximal and distal tubular segments of …

The 21-amino acid peptide endothelin-1 (ET-1) is the predominant isoform of the endothelin
peptide family, which includes ET-2, ET-3, and ET-4. It exerts various biological effects …

Hirschsprung's disease (HSCR) is characterized by an absence of enteric ganglia in the
distal colon and a failure of innervation in the gastrointestinal tract. We recently mapped a …

Endothelins (ET) produce endothelium-dependent vasodilation through nitric oxide (NO)
synthesis. The present study was designed to elucidate the cellular mechanism by which ET …

▪ Abstract In this article, we review the basic pharmacological and biochemical features of
endothelin and the pathophysiological roles of endothelin in cardiovascular diseases …

Following the first report on the identification of endothelin (ET), an increasing body of work
has accumulated on this endothelium-derived 22-amino acid vasoconstictor peptide …

Endothelin-1 (ET-1) is a 21-amino acid peptide that potently modulates renal function. ET-1
is produced by, and binds to, most renal cell types. ET-1 exerts a wide range of biologic …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
44260042&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

We have recently shown that mechanical stress induces cardiomyocyte hypertrophy partly
through the enhanced secretion of angiotensin II (ATII). Endothelin-1 (ET-1) has been …