[HTML][HTML] Enkephalins and Pain Modulation: Mechanisms of Action and Therapeutic Perspectives

M García-Domínguez - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
Enkephalins, a subclass of endogenous opioid peptides, play a pivotal role in pain
modulation. Enkephalins primarily exert their effects through opioid receptors located widely …

[HTML][HTML] Management of Fibromyalgia: Novel Nutraceutical Therapies Beyond Traditional Pharmaceuticals

A Antonelli, M Bianchi, EJ Fear, L Giorgi, L Rossi - Nutrients, 2025 - mdpi.com
The pathophysiology of fibromyalgia, a condition that causes chronic pain throughout the
body, involves abnormal pain signaling, genetic predispositions, and abnormal …

Problem-oriented coping and resilience among Fibromyalgia patients who live under security threats and have undergone a Fibrotherapy intervention program

L Cohen-Biton, D Buskila… - Psychology, Health & …, 2024 - Taylor & Francis
Our study examined the association between problem-focused coping and resilience among
fibromyalgia (FM) patients who live under constant security threats. Resilience is a coping …

[HTML][HTML] Outlining the psychological profile of persistent depression in fibromyalgia patients through Personality Assessment Inventory (PAI)

A Doreste, J Pujol, E Penelo, V Pérez… - European Journal of …, 2025 - mdpi.com
Background: Fibromyalgia (FM) is a complex condition marked by increased pain sensitivity
and central sensitization. Studies often explore the link between FM and depressive anxiety …

[HTML][HTML] Pregabalin produces analgesia in males but not females in an animal model of chronic widespread muscle pain

AN Plumb, K Hayashi, A Janowski, A Smith… - Pain …, 2024 - journals.lww.com
Objectives: The purpose of our study was to investigate potential sex differences in the
analgesic efficacy of pregabalin that may contribute to disparities in human outcomes …

Exploring the Relationship between Diamine Oxidase and Psychotropic Medications in Fibromyalgia Treatment, Finding No Reduction in Diamine Oxidase Levels and …

Y Tobajas, M Alemany-Fornés, I Samarra… - Journal of Clinical …, 2024 - mdpi.com
Background: Histamine intolerance manifests when there is an imbalance between the
production of histamine and the body's capacity to metabolise it. Within the gastrointestinal …

[HTML][HTML] Efficacy and safety of transcranial direct current stimulation in the treatment of fibromyalgia: A systematic review and meta-analysis

CL Yang, Y Qu, JP Huang, TT Wang, H Zhang… - Neurophysiologie …, 2024 - Elsevier
Objectives To update a systematic review of the efficacy and safety of transcranial direct
current stimulation (tDCS) for analgesia, for antidepressant effects, and to reduce the impact …

[HTML][HTML] Effects of Traditional Chinese Exercises in Fibromyalgia Syndrome: A Meta-Analysis of Randomized Controlled Trials

H Zhang, X Zhang, Y Wang, X Sun, S Li, J Zhang… - … Therapies in Medicine, 2024 - Elsevier
Objectives To explore the efficacy and safety of five traditional Chinese exercises (TCEs) in
patients with fibromyalgia syndrome (FMS). Methods The PubMed, Embase, Scopus …

[HTML][HTML] Electroacupuncture Regulates Cannabinoid Receptor 1 Expression in a Mouse Fibromyalgia Model: Pharmacological and Chemogenetic Modulation

YA Yeh, HC Hsu, MC Lin, TS Chen, WC Lin, HM Huang… - Life, 2024 - mdpi.com
Fibromyalgia is a chronic illness usually accompanied by long-lasting, general pain
throughout the body, often accompanied by anxiety, depression, fatigue, and sleep …

[HTML][HTML] The efficacy and safety of telerehabilitation for fibromyalgia: systematic review and meta-analysis of randomized controlled trials

YQ Wu, Y Long, WJ Peng, C Gong, YQ Liu… - Journal of Medical …, 2023 - jmir.org
Background Fibromyalgia is a chronic pain syndrome characterized by persistent and
widespread musculoskeletal pain. Telerehabilitation is a promising treatment for patients …