Supervised machine learning for population genetics: a new paradigm

DR Schrider, AD Kern - Trends in Genetics, 2018 - cell.com
As population genomic datasets grow in size, researchers are faced with the daunting task
of making sense of a flood of information. To keep pace with this explosion of data …

Uncovering ecological state dynamics with hidden Markov models

BT McClintock, R Langrock, O Gimenez, E Cam… - Ecology …, 2020 - Wiley Online Library
Ecological systems can often be characterised by changes among a finite set of underlying
states pertaining to individuals, populations, communities or entire ecosystems through time …

Population genomics of parallel adaptation in threespine stickleback using sequenced RAD tags

PA Hohenlohe, S Bassham, PD Etter, N Stiffler… - PLoS …, 2010 - journals.plos.org
Next-generation sequencing technology provides novel opportunities for gathering genome-
scale sequence data in natural populations, laying the empirical foundation for the evolving …

The unreasonable effectiveness of convolutional neural networks in population genetic inference

L Flagel, Y Brandvain… - Molecular biology and …, 2019 - academic.oup.com
Population-scale genomic data sets have given researchers incredible amounts of
information from which to infer evolutionary histories. Concomitant with this flood of data …

Selective sweeps

W Stephan - Genetics, 2019 - academic.oup.com
For almost 20 years, many inference methods have been developed to detect selective
sweeps and localize the targets of directional selection in the genome. These methods are …

Detecting signatures of selection through haplotype differentiation among hierarchically structured populations

MI Fariello, S Boitard, H Naya, M SanCristobal… - Genetics, 2013 - academic.oup.com
The detection of molecular signatures of selection is one of the major concerns of modern
population genetics. A widely used strategy in this context is to compare samples from …

Using population genomics to detect selection in natural populations: key concepts and methodological considerations

PA Hohenlohe, PC Phillips… - International journal of …, 2010 - journals.uchicago.edu
Natural selection shapes patterns of genetic variation among individuals, populations, and
species, and it does so differentially across genomes. The field of population genomics …

Landmarks in the history of selective sweeps

M Panigrahi, D Rajawat, SS Nayak, K Ghildiyal… - Animal …, 2023 - Wiley Online Library
Half a century ago, a seminal article on the hitchhiking effect by Smith and Haigh
inaugurated the concept of the selection signature. Selective sweeps are characterised by …

Detecting signatures of positive selection in non-model species using genomic data

H Weigand, F Leese - Zoological journal of the Linnean Society, 2018 - academic.oup.com
Understanding how natural selection shapes genetic variation in populations is of
paramount importance in evolutionary biology. Affordable high-throughput sequencing now …

Detecting recent selective sweeps while controlling for mutation rate and background selection

CD Huber, M DeGiorgio, I Hellmann… - Molecular …, 2016 - Wiley Online Library
A composite likelihood ratio test implemented in the program sweepfinder is a commonly
used method for scanning a genome for recent selective sweeps. sweepfinder uses …