Any aspect of cell activity is regulated by extracellular signals that are recognized, decoded,
and transduced inside the cell via different classes of plasma membrane receptors. 1À3 G …

A large section of cellular proteins in both prokaryotic and eukaryotic systems have
oligomeric property. Intently, oligomerization of protein is an invaluable phenomenon from …

Ion channels are integral membrane proteins that control movement of ions into or out of
cells. They are key components in a wide range of biological processes. Different types of …

Rapid expansion of available data about G Protein Coupled Receptor (GPCR)
dimers/oligomers over the past few years requires an effective system to organize this …

Receptology has been complicated with enhancements in our knowledge of G‐protein‐
coupled‐receptor (GPCR) biochemistry. This complexity is exemplified by the pharmacology …

GPCR oligomerization has emerged as a hot topic in the GPCR field in the last years.
Receptors that are part of these oligomers can influence each other's function, although it is …

Highlights•GPCRs are key targets for cell signaling and are of great interest to both the
pharmaceutical industry and academy.•In this review, recent approaches and applications of …

The available evidence for receptor–receptor interactions between adenosine A2A,
dopamine D2, cannabinoid CB1, and metabotropic glutamate mGlu5 receptors (A2A, D2 …

Recent research has unveiled the complexity of mechanisms involved in G protein-coupled
receptor (GPCR) functioning in which receptor dimerization/oligomerization may play an …

ABSTRACT G Protein‐Coupled Receptors (GPCRs) are important pharmaceutical targets.
More than 30% of currently marketed pharmaceutical medicines target GPCRs. Numerous …