Recent research has shown that state reporting to human rights monitoring bodies is
associated with improvements in rights practices, calling into question earlier claims that self …

Calcineurin is a eukaryotic Ca2+-and calmodulin-dependent serine/threonine protein
phosphatase. It is a heterodimeric protein consisting of a catalytic subunit calcineurin A …

In response to numerous pathologic stimuli, the myocardium undergoes a hypertrophic
response characterized by increased myocardial cell size and activation of fetal cardiac …

The 'EF-hand'Ca2+-binding motif plays an essential role in eukaryotic cellular signalling,
and the proteins containing this motif constitute a large and functionally diverse family. The …

Abstract Background Calcium (Ca 2+) oscillations are ubiquitous signals present in all cells
that provide efficient means to transmit intracellular biological information. Either …

While changes in gene expression are critical for many brain functions, including long-term
memory, little is known about the cellular processes that mediate stimulus–transcription …

The role of protein phosphatases in the regulation of cellular processes is now well
established (1, 2). Calcineurin (also called protein phosphatase 2B), a major calmodulin …

Calcineurin is a calcium activated protein phosphatase with a major role in calcium
signaling in diverse cells and organs and clinical importance as the target of the …

The solution structure of Ca2+-free calmodulin has been determined by NMR spectroscopy,
and is compared to the previously reported structure of the Ca2+-saturated form. The …

CALCINEURIN (CaN) is a calcium-and ca 1modulin-dependent protein serine/threonine
phosphatase which is critical for several important cellular processes, including T-cell …