More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …

A characteristic feature of host responses to helminth infections is the development of
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …

Plasmacytoid dendritic cells (pDCs) have been shown to play an important role during
immune responses, ranging from initial viral control through the production of type I …

Early-life establishment of tolerance to commensal bacteria at barrier surfaces carries
enduring implications for immune health but remains poorly understood. Here, we showed …

Males and females exhibit profound differences in immune responses and disease
susceptibility. However, the factors responsible for sex differences in tissue immunity remain …

Conventional dendritic cells (cDCs) include functionally and phenotypically diverse
populations, such as cDC1s and cDC2s. The latter population has been variously …

Keloids, characterized by skin fibrosis and excessive accumulation of extracellular matrix,
remain a therapeutic challenge. In this study, we systematically capture the cellular …

Atopic dermatitis (AD) is a chronic, inflammatory, intensely pruritic skin disorder associated
with significant patient burden. Interleukin (IL)‐13 is a cytokine that acts as a driver of …

Psoriasis is a common chronic inflammatory skin disease. The diversity and heterogeneity of
immune cells in human skin have been studied in recent years, but the spatial distribution of …

The thymus contains a diversity of dendritic cells (DCs) that exist in defined locations and
have different antigen-processing and-presenting features. This suggests that they play …