Epigenetics involves a series of mechanisms that entail histone and DNA covalent
modifications and non-coding RNAs, and that collectively contribute to programing cell …

As a chronic metabolic disease affecting epidemic proportions worldwide, the pathogenesis
of Nonalcoholic Fatty Liver Disease (NAFLD) is not clear yet. There is also a lack of precise …

Background: There is evidence that vitamin B12 and associated metabolite levels are
changed in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis …

Arsenic, a common environmental hazard, is a risk factor for nonalcoholic fatty liver disease
(NAFLD). However, the mechanism remains unclear. Here, we found that chronic exposure …

Despite progress describing the effects of persistent organic pollutants (POPs) on the central
nervous system, the effect of POPs on enteric nervous system (ENS) function remains …

Gut dysbiosis with disrupted enterohepatic bile acid metabolism is commonly associated
with non-alcoholic fatty liver disease (NAFLD) and recapitulated in a NAFLD-phenotype …

Ligand activation of the aryl hydrocarbon receptor (AHR) accelerates keratinocyte
differentiation and the formation of the epidermal permeability barrier. Several classes of …

The persistent environmental aryl hydrocarbon receptor agonist and hepatotoxin TCDD (2,
3, 7, 8-tetrachlorodibenzo-p-dioxin) induces hepatic lipid accumulation (steatosis) …

Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) has been associated with the
induction of oxidative stress and the progression of steatosis to steatohepatitis with fibrosis. It …

Abstract Previously we demonstrated that 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
suppressed experimental autoimmune encephalomyelitis (EAE), a model to study multiple …