More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …

Immunotherapies targeting conventional T cells have revolutionized systemic treatment for
many cancers, yet only a subset of patients benefit from these approaches. A better …

The cellular landscape of the human intestinal tract is dynamic throughout life, developing in
utero and changing in response to functional requirements and environmental exposures …

The human lung plays vital roles in respiration, host defense, and basic physiology. Recent
technological advancements such as single-cell RNA sequencing and genetic lineage …

The functional diversity of natural killer (NK) cell repertoires stems from differentiation,
homeostatic, receptor–ligand interactions and adaptive-like responses to viral infections. In …

Group 1 innate lymphoid cells (ILC1s) are cytotoxic and interferon gamma-producing
lymphocytes lacking antigen-specific receptors, which include ILC1s and natural killer (NK) …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Natural killer (NK) cells and type 1 innate lymphoid cells (ILC1s) are populations of non-T,
non-B lymphocytes in peripheral tissues. Although NK and ILC1 subsets have been …

Group 2 innate lymphoid cells (ILC2s) represent innate homologs of type 2 helper T cells
(TH2) that participate in immune defense and tissue homeostasis through production of type …

Innate lymphoid cells (ILCs) are critical effectors of innate immunity and inflammation, whose
development and activation pathways make for attractive therapeutic targets. However …