• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Health professionals are encouraged to take the ESC/EACTS Guidelines fully into account
when exercising their clinical judgment, as well as in the determination and the …

Background Rheumatic heart disease affects more than 40.5 million people worldwide and
results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart …

Heart failure (HF) is a heterogeneous clinical syndrome marked by substantial morbidity and
mortality. The natural history of HF is well established; however, epidemiological data are …

Objectives Cardiovascular disease (CVD) is leading cause of death in China. We aimed to
provide national and subnational estimates and its change of premature mortality burden of …

Rheumatic heart disease (RHD) is the result of episodes of acute rheumatic fever with
valvular (and other cardiac) damage caused by an abnormal immune response to group A …

Group A Streptococcus (GAS) causes superficial and invasive infections and immune
mediated post-infectious sequalae (including acute rheumatic fever/rheumatic heart …

This review discusses recent advancements in the field of valvular heart disease. Topics
covered include recognition of the impact of atrial fibrillation on development and …

Nearly a century after rheumatic fever (RF) and rheumatic heart disease (RHD) was
eradicated from the developed world, the disease remains endemic in many low-and middle …

The increased cardiovascular (CV) risk among patients with autoimmune rheumatic
diseases, such as arthritides and connective tissue diseases, has been extensively …