Toll-like receptors (TLRs) are highly conserved trans-membrane proteins that play an
important role in the detection and recognition of microbial pathogens. The key product of …

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-Tof-MS)
has recently become a popular and versatile method to analyze macromolecules from …

Background. The clinical spectrum of respiratory syncytial virus (RSV) bronchiolitis in
previously healthy infants is extremely variable. Thus, it is likely that factors such as genetic …

Objective To review how biotrauma leads to the development of multiple system organ
failure (MSOF). Design and setting Published articles on experimental and clinical studies …

Abstract Toll-like receptor 4 (TLR4) is an important pathogen recognition receptor that
recognizes mainly lipopolysaccharide (LPS) of Gram-negative bacteria, but also structures …

Background Evidence that a deficient innate immune response toward the bacterial flora of
the gut plays a role in the pathogenesis of inflammatory bowel disease (IBD) is growing. This …

The control of Mycobacterium tuberculosis infection depends on recognition of the pathogen
and the activation of both the innate and adaptive immune responses. Toll-like receptors …

TLR4 is the signal-transducing receptor for structurally diverse microbial molecules such as
bacterial LPS, respiratory syncytial virus fusion (F) protein, and chlamydial heat shock …

Respiratory syncytial virus (RSV) is a leading cause of infant mortality worldwide. Although
anti-RSV Ab prophylaxis has greatly reduced infant mortality in the United States, there is …

Inflammation has been implicated as an etiological factor in several human cancers.
Growing evidence suggests that chronic inflammation may also play a role in the etiology of …