Frustration, function and folding

DU Ferreiro, EA Komives, PG Wolynes - Current opinion in structural …, 2018 - Elsevier
Natural protein molecules are exceptional polymers. Encoded in apparently random strings
of amino-acids, these objects perform clear physical tasks that are rare to find by simple …

Molecular regulation of lactation: The complex and requisite roles for zinc

S Lee, SL Kelleher - Archives of Biochemistry and Biophysics, 2016 - Elsevier
Lactation provides many health benefits to the nursing infant and breastfeeding mother. In
order to successfully breastfeed, the mammary gland must expand and differentiate to …

Molecular dynamics simulations of reduced and oxidized TFIIIA zinc fingers free and interacting with 5S RNA

A Dreab, CA Bayse - Journal of Chemical Information and …, 2022 - ACS Publications
Interactions of zinc finger (ZF) proteins with nucleic acids and proteins play an important role
in DNA transcription and repair, biochemical recognition, and protein regulation. The …

Atomistic analysis of ToxN and ToxI complex unbinding mechanism

G Hu, X Yu, Y Bian, Z Cao, S Xu, L Zhao, B Ji… - International Journal of …, 2018 - mdpi.com
ToxIN is a triangular structure formed by three protein toxins (ToxNs) and three specific
noncoding RNA antitoxins (ToxIs). To respond to stimuli, ToxI is preferentially degraded …

Binding modes of Bcl-2 homology 3 (BH3) peptides with anti-apoptotic protein A1 and redesign of peptide inhibitors: a computational study

Y Chen, J Wang, J Zhang, W Wang - Journal of Biomolecular …, 2018 - Taylor & Francis
The interaction between protein and peptide ligand is a challenging problem in molecular
biology and drug design. The binding of the Bcl-2 homology 3 (BH3) peptide to the anti …

The key role of electrostatic interactions in the induced folding in RNA recognition by DCL1-A

L Zhao, IP Suarez, DF Gauto, RM Rasia… - Physical Chemistry …, 2018 - pubs.rsc.org
The intrinsically disordered protein domain DCL1-A is the first report of a complete double
stranded RNA binding domain folding upon binding. DCL1-A recognizes the dsRNA by …

A multiscale approach to simulating the conformational properties of unbound multi‐C2H2 zinc finger proteins

L Liu, RC Wade, DW Heermann - Proteins: Structure, Function …, 2015 - Wiley Online Library
The conformational properties of unbound multi‐Cys2His2 (mC2H2) zinc finger proteins, in
which zinc finger domains are connected by flexible linkers, are studied by a multiscale …

Протеомный профиль мочи здорового человека в норме и при действии факторов космического полета

ЛХ Пастушкова - Москва, 2015 - static.freereferats.ru
Защита диссертации состоется «8» июля 2015 г. В 10 часов на заседании
диссертационного совета Д 002.111. 01, созданного на базе Федерального …

Implications of Metal Coordination in Damage and Recognition of Nucleic Acids and Lipid Bilayers

A Dreab - 2022 - search.proquest.com
Metal ions have a myriad of biological functions from structural stability to enzymatic (de)
activation and metabolic electron transfer. Redox-active metals also mediate the formation of …