Fatty acid-induced lipotoxicity in pancreatic beta-cells during development of type 2 diabetes

YS Oh, GD Bae, DJ Baek, EY Park… - Frontiers in …, 2018 - frontiersin.org
Type 2 diabetes is caused by chronic insulin resistance and progressive decline in beta-cell
function. Optimal beta-cell function and mass is essential for glucose homeostasis and beta …

The role of short-chain fatty acids in health and disease

J Tan, C McKenzie, M Potamitis, AN Thorburn… - Advances in …, 2014 - Elsevier
There is now an abundance of evidence to show that short-chain fatty acids (SCFAs) play an
important role in the maintenance of health and the development of disease. SCFAs are a …

Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance

M Bionaz, E Vargas-Bello-Pérez, S Busato - Journal of Animal Science …, 2020 - Springer
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …

The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer

MM Kaczmarczyk, MJ Miller, GG Freund - Metabolism, 2012 - Elsevier
Dietary fiber (DF) is deemed to be a key component in healthy eating. DF is not a static
collection of undigestible plant materials that pass untouched or unencumbered through the …

Management of type 2 diabetes: new and future developments in treatment

AA Tahrani, CJ Bailey, S Del Prato, AH Barnett - The Lancet, 2011 - thelancet.com
The increasing prevalence, variable pathogenesis, progressive natural history, and
complications of type 2 diabetes emphasise the urgent need for new treatment strategies …

Bacteria within the gastrointestinal tract microbiota correlated with improved growth and feed conversion: challenges presented for the identification of performance …

D Stanley, RJ Hughes, MS Geier… - Frontiers in microbiology, 2016 - frontiersin.org
Identification of bacteria associated with desirable productivity outcomes in animals may
offer a direct approach to the identification of probiotic bacteria for use in animal production …

β-glucans and cholesterol

P Sima, L Vannucci, V Vetvicka - … journal of molecular …, 2018 - spandidos-publications.com
Hypercholesterolemia is one of primary risk factors of cardiovascular disease, together with
metabolic syndrome, hypertension and diabetes. Although progress has been made, the …

The shift work and health research agenda: considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and …

AC Reynolds, JL Paterson, SA Ferguson… - Sleep medicine …, 2017 - Elsevier
Prevalence and impact of metabolic disease is rising. In particular, overweight and obesity
are at epidemic levels and are a leading health concern in the Western world. Shift work …

Free fatty acid receptors (FFARs) in adipose: physiological role and therapeutic outlook

S Al Mahri, SS Malik, M Al Ibrahim, E Haji, G Dairi… - Cells, 2022 - mdpi.com
Fatty acids (FFAs) are important biological molecules that serve as a major energy source
and are key components of biological membranes. In addition, FFAs play important roles in …

A high-fat diet promotes depression-like behavior in mice by suppressing hypothalamic PKA signaling

E Vagena, JK Ryu, B Baeza-Raja, NM Walsh… - Translational …, 2019 - nature.com
Obesity is associated with an increased risk of depression. The aim of the present study was
to investigate whether obesity is a causative factor for the development of depression and …