Pulpal and periapical diseases account for a large proportion of dental visits, the current
treatments for which are root canal therapy (RCT) and pulp revascularisation. Despite the …

Currently, the challenge in dentistry is to revitalize dental pulp by utilizing tissue engineering
technology; thus, a biomaterial is needed to facilitate the process. One of the three essential …

Objectives Pulp regeneration brings big challenges for clinicians, and vascularization is
considered as its determining factor. We previously accomplished pulp regeneration with …

A randomized controlled phase I/II clinical trial was designed to evaluate the safety and
efficacy of encapsulated human umbilical cord mesenchymal stem cells in a plasma-derived …

Regenerative dentistry has come a long way from pulp capping to pulp regeneration
research, which aims to regenerate the pulp-dentin complex and restore its functions …

Dental pulp, plays an indispensable role in maintaining homeostasis of the tooth. Pulp
necrosis always causes tooth nutrition deficiency and abnormal root development, which …

Aim of the study: Deep carious lesions may cause irreversible pulpitis and the current
endodontic treatment typically removes the whole dental pulp tissue, which finally reduces …

Pulp loss is accompanied by the functional impairment of defense, sensory, and nutrition
supply. The approach based on endogenous stem cells is a potential strategy for pulp …

Background Pulp–dentine complex regeneration via tissue engineering is a developing
treatment modality that aims to replace necrotic pulps with newly formed healthy tissue …

Maintaining dental pulp vitality and preventing tooth loss are two challenges in endodontic
treatment. A tooth lacking a viable pulp loses its defense mechanism and regenerative …