Role of heavy metals (copper (Cu), arsenic (As), cadmium (Cd), iron (Fe) and lithium (Li)) induced neurotoxicity

B Vellingiri, A Suriyanarayanan, P Selvaraj… - Chemosphere, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative condition characterized by the dopamine
(DA) neuronal loss in the substantia nigra. PD impairs motor controls symptoms such as …

The molecular mechanisms of neuroinflammation in Alzheimer's disease, the consequence of neural cell death

SB Choi, S Kwon, JH Kim, NH Ahn, JH Lee… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is accompanied by neural cell loss and memory deficit. Neural cell
death, occurring via apoptosis and autophagy, is widely observed in the AD brain in addition …

Exposure to environmental arsenic and emerging risk of Alzheimer's disease: perspective mechanisms, management strategy, and future directions

MA Rahman, MA Hannan, MJ Uddin, MS Rahman… - Toxics, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prevailing neurodegenerative diseases,
characterized by memory dysfunction and the presence of hyperphosphorylated tau and …

[HTML][HTML] Emodin promotes autophagy and prevents apoptosis in sepsis-associated encephalopathy through activating BDNF/TrkB signaling

LL Gao, ZH Wang, YH Mu, ZL Liu, L Pang - Pathobiology, 2022 - karger.com
Objective: Sepsis-associated encephalopathy (SAE) is a severe and common complication
of sepsis and can induce cognitive dysfunction and apoptosis of neurons and …

Proteomic study on the mechanism of arsenic neurotoxicity in the rat cerebral cortex and the protective mechanism of dictyophora polysaccharides against arsenic …

X Zhang, H Yang, Y Wang, J Zhang… - ACS Chemical …, 2023 - ACS Publications
Arsenic (As) is a toxic element, and long-term exposure to As can cause neurotoxicity. The
bioactive natural compound Dictyophora polysaccharide (DIP) from edible plants has been …

Heavy metals exposure and Alzheimer's disease: Underlying mechanisms and advancing therapeutic approaches

NA Althobaiti - Behavioural Brain Research, 2024 - Elsevier
Heavy metals such as lead, cadmium, mercury, and arsenic are prevalent in the
environment due to both natural and anthropogenic sources, leading to significant public …

Arsenic and cancer: Evidence and mechanisms

RM Speer, X Zhou, LB Volk, KJ Liu… - Advances in Pharmacology, 2023 - Elsevier
Arsenic is a potent carcinogen and poses a significant health concern worldwide. Exposure
occurs through ingestion of drinking water and contaminated foods and through inhalation …

Detoxification of selenium yeast on mycotoxins and heavy metals: a review

H Sun, J Chen, D Xiong, M Long - Biological Trace Element Research, 2023 - Springer
Mycotoxins are secondary metabolites produced by specific fungi. More than 400 different
mycotoxins are known in the world, and the concentration of these toxins in food and feed …

Valence-dependent immune responses of earthworm coelomocytes: Toxicity pathways and molecular mechanisms of As (III) and As (V)-induced immunotoxicity

T Wang, X Li, F He, S Guo, F Du, H Song… - Science of The Total …, 2024 - Elsevier
Epidemiological studies in inorganic arsenic (iAs) exposure populations have offered
convincing evidence that exposure to arsenite (As (III)) and arsenate (As (V)) are linked to …

Inhibition of XPO1 with KPT-330 induces autophagy-dependent apoptosis in gallbladder cancer by activating the p53/mTOR pathway

C Zhao, Z Yang, J Zhang, O Li, S Liu, C Cai… - Journal of Translational …, 2022 - Springer
Background Gallbladder cancer (GBC) is a highly aggressive malignant cancer in the biliary
system with poor prognosis. XPO1 (chromosome region maintenance 1 or CRM1) mediates …