Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Self-assembling peptides could be considered a novel class of agents able to harvest an
array of micro/nanostructures that are highly attractive in the biomedical field. By modifying …

ZED1227 is a small molecule tissue transglutaminase (TG2) inhibitor. The compound
selectively binds to the active state of TG2, forming a stable covalent bond with the cysteine …

The complex interplay between dietary factors, inflammation, and macrophage polarization
is pivotal in the pathogenesis and progression of chronic liver diseases (CLDs). Omega-3 …

Biomaterials are of significant importance in biomedical applications as these biological
macromolecules have moderately replaced classical tissue grafting techniques owing to its …

Type 2 transglutaminase (TG2) is the main autoantigen in coeliac disease (CD), a
widespread inflammatory enteropathy caused by the ingestion of gluten-containing cereals …

Proteomics is a powerful approach to study the molecular mechanisms of cancer. In this
study, we aim to characterize the proteomic profile of gastric cancer (GC) in patients with …

Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high
heterogeneity that drives tumor aggressiveness. Melanoma plasticity consists of two distinct …

Worldwide, up to 20% of children and adolescents experience mental disorders, which are
the leading cause of disability in young people. Research shows that serum zonulin levels …

Tissue transglutaminase (transglutaminase type 2; TG2) is the most ubiquitously expressed
member of the transglutaminase family (EC 2.3. 2.13) that catalyzes specific post …