Alcohol use disorder (AUD) is a chronic, relapsing brain disorder, characterized by
compulsive alcohol seeking and disrupted brain function. In individuals with AUD …

Individuals with alcohol use disorder (AUD) show elevated brain metabolism of acetate at
the expense of glucose. We hypothesized that a shift in energy substrates during withdrawal …

Although the cause of progressive neurodegeneration is often unclear, neuronal death can
occur through several mechanisms. In conditions such as Alzheimer's or alcohol use …

Sleep disturbances are prominent in patients with alcohol use disorder (AUD) and predict
relapse. So far, the mechanisms underlying sleep disruptions in AUD are poorly understood …

This study aimed to investigate structural and functional alterations of the reward system and
the neurobiology of craving in alcohol use disorder (AUD). We hypothesized reduced …

Here we assessed changes in subcortical volumes in alcohol use disorder (AUD). A simple
morphometry-based classifier (MC) was developed to identify subcortical volumes that …

Gene expression studies offer promising opportunities to better understand the processes
underlying alcohol use disorder (AUD). As cell types differ in their function, gene expression …

Several cross-sectional investigations reported widespread cortical thinning in those with
alcohol use disorder (AUD). The few longitudinal studies investigating cortical thickness …

Upon both acute and prolonged alcohol intake, the brain undergoes a metabolic shift
associated with increased acetate metabolism and reduced glucose metabolism, which …

Alcohol induces neuroinflammation but its role in cognitive impairment and impulsivity in
alcohol use disorder (AUD) has been poorly investigated. We used proton magnetic …