Advances in extracellular vesicle nanotechnology for precision theranostics

Q Wu, S Fu, H Xiao, J Du, F Cheng, S Wan… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …

Extracellular vesicle-based therapeutics: Extracellular vesicles as therapeutic targets and agents

Y Takahashi, Y Takakura - Pharmacology & Therapeutics, 2023 - Elsevier
Extracellular vesicles (EVs) are cell-derived membrane vesicles composed of a lipid bilayer.
EVs contain biological molecules, such as nucleic acids, lipids, and proteins. As these …

Exosomes as rheumatoid arthritis diagnostic biomarkers and therapeutic agents

R Heydari, F Koohi, M Rasouli, K Rezaei… - Vaccines, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder that causes systemic
inflammation, autoimmunity, and joint abnormalities that result in permanent disability …

Research development on exosome separation technology

WM Xu, A Li, JJ Chen, EJ Sun - The Journal of Membrane Biology, 2023 - Springer
Exosomes are special extracellular vesicles secreted by cells, which are of great
significance in the basic research of life science and clinical application and has become a …

Comprehensive review of MS‐based studies on N‐glycoproteome and N‐glycome of extracellular vesicles

Y Li, J Wang, W Chen, H Lu, Y Zhang - Proteomics, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer‐enclosed particles that can be released by all
type of cells. Whereas, as one of the most common post‐translational modifications …

Milk exosomes: next-generation agents for delivery of anticancer drugs and therapeutic nucleic acids

AM Timofeeva, AP Paramonik, SS Sedykh… - International Journal of …, 2023 - mdpi.com
Exosomes are nanovesicles 40–120 nm in diameter secreted by almost all cell types and
providing humoral intercellular interactions. Given the natural origin and high …

Extracellular vesicles in cancer: challenges and opportunities for clinical laboratories

Á González, S López-Borrego, A Sandúa… - Critical Reviews in …, 2024 - Taylor & Francis
Extracellular vesicles (EVs) are nano-sized particles secreted by most cells. They transport
different types of biomolecules (nucleic acids, proteins, and lipids) characteristic of their …

[HTML][HTML] Microfluidic-based technologies in cancer liquid biopsy: Unveiling the role of horizontal gene transfer (HGT) materials

SH Javanmard, L Rafiee, MB Najafi, D Khorsandi… - Environmental …, 2023 - Elsevier
Liquid biopsy includes the isolating and analysis of non-solid biological samples enables us
to find new ways for molecular profiling, prognostic assessment, and better therapeutic …

Exosomal plasma gelsolin is an immunosuppressive mediator in the ovarian tumor microenvironment and a determinant of chemoresistance

T Onuma, M Asare-Werehene, Y Yoshida, BK Tsang - Cells, 2022 - mdpi.com
Ovarian Cancer (OVCA) is the most fatal gynecologic cancer and has a 5-year survival rate
less than 45%. This is mainly due to late diagnosis and drug resistance. Overexpression of …

Microfluidic device using metallic nanostructure arrays for the isolation, detection, and purification of exosomes

YS Hsiao, CW Chen, R Haliq, PM Yiu, PI Wu… - Journal of Alloys and …, 2023 - Elsevier
Microfluidic devices are widely used in disease detection and specimen separation due to
their low cost, rapid processing, and the ability to use even minuscule samples. This study …