Demographic noise can reverse the direction of deterministic selection

GWA Constable, T Rogers… - Proceedings of the …, 2016 - National Acad Sciences
Deterministic evolutionary theory robustly predicts that populations displaying altruistic
behaviors will be driven to extinction by mutant cheats that absorb common benefits but do …

Intrinsic noise in systems with switching environments

PG Hufton, YT Lin, T Galla, AJ McKane - Physical Review E, 2016 - APS
We study individual-based dynamics in finite populations, subject to randomly switching
environmental conditions. These are inspired by models in which genes transition between …

Slow expanders invade by forming dented fronts in microbial colonies

H Lee, J Gore, KS Korolev - Proceedings of the National …, 2022 - National Acad Sciences
Most organisms grow in space, whether they are viruses spreading within a host tissue or
invasive species colonizing a new continent. Evolution typically selects for higher expansion …

Mapping of the stochastic Lotka-Volterra model to models of population genetics and game theory

GWA Constable, AJ McKane - Physical Review E, 2017 - APS
The relationship between the M-species stochastic Lotka-Volterra competition (SLVC) model
and the M-allele Moran model of population genetics is explored via timescale separation …

Tuning spatial profiles of selection pressure to modulate the evolution of drug resistance

MG De Jong, KB Wood - Physical review letters, 2018 - APS
Spatial heterogeneity plays an important role in the evolution of drug resistance. While
recent studies have indicated that spatial gradients of selection pressure can accelerate …

Models of genetic drift as limiting forms of the Lotka-Volterra competition model

GWA Constable, AJ McKane - Physical review letters, 2015 - APS
The relationship between the Moran model and stochastic Lotka-Volterra competition
(SLVC) model is explored via time scale separation arguments. For neutral systems the two …

[HTML][HTML] Daily forecasting of regional epidemics of Coronavirus Disease with Bayesian uncertainty quantification, United States

YT Lin, J Neumann, EF Miller, RG Posner… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
To increase situational awareness and support evidence-based policymaking, we
formulated a mathematical model for coronavirus disease transmission within a regional …

Effects of niche overlap on coexistence, fixation and invasion in a population of two interacting species

M Badali, A Zilman - Royal Society open science, 2020 - royalsocietypublishing.org
Synergistic and antagonistic interactions in multi-species populations—such as resource
sharing and competition—result in remarkably diverse behaviours in populations of …

Influence of invasion on natural selection in dispersal-structured populations

DN Maeso, M Patriarca, E Heinsalu - Physica A: Statistical Mechanics And …, 2022 - Elsevier
We investigate how initial and boundary conditions influence the competition dynamics and
outcome in dispersal-structured populations. The study is carried out through numerical …

Exploiting fast-variables to understand population dynamics and evolution

GWA Constable, AJ McKane - Journal of Statistical Physics, 2018 - Springer
We describe a continuous-time modelling framework for biological population dynamics that
accounts for demographic noise. In the spirit of the methodology used by statistical …