Liking, wanting, and the incentive-sensitization theory of addiction.

KC Berridge, TE Robinson - American Psychologist, 2016 - psycnet.apa.org
Rewards are both “liked” and “wanted,” and those 2 words seem almost interchangeable.
However, the brain circuitry that mediates the psychological process of “wanting” a particular …

Amphetamine-induced dopamine release in rat: Whole-brain spatiotemporal analysis with [11C]raclopride and positron emission tomography

J Johansson, M Ericsson, J Axelsson… - Journal of Cerebral …, 2024 - journals.sagepub.com
Whole-brain mapping of drug effects are needed to understand the neural underpinnings of
drug-related behaviors. Amphetamine administration is associated with robust increases in …

Partial-volume correction increases estimated dopamine D2-like receptor binding potential and reduces adult age differences

CT Smith, JL Crawford, LC Dang… - Journal of Cerebral …, 2019 - journals.sagepub.com
The relatively modest spatial resolution of positron emission tomography (PET) increases
the likelihood of partial volume effects such that binding potential (BPND) may be …

The impact of common dopamine D2 receptor gene polymorphisms on D2/3 receptor availability: C957T as a key determinant in putamen and ventral striatum

CT Smith, LC Dang, JW Buckholtz, AM Tetreault… - Translational …, 2017 - nature.com
Dopamine function is broadly implicated in multiple neuropsychiatric conditions believed to
have a genetic basis. Although a few positron emission tomography (PET) studies have …

PET imaging of dopamine-D2 receptor internalization in schizophrenia

JJ Weinstein, E van de Giessen, RJ Rosengard… - Molecular …, 2018 - nature.com
Recent genetic, molecular and post-mortem studies suggest impaired dopamine (DA)-D2
receptor (D2R) trafficking in patients with schizophrenia (SZ). Imaging and preclinical …

Striatal activation to monetary reward is associated with alcohol reward sensitivity

M Radoman, NA Crane, SM Gorka, J Weafer… - …, 2021 - nature.com
One well-known phenotypic risk factor for the development of alcohol use disorder is
sensitivity to the rewarding effects of alcohol. In the present study, we examined whether …

Accentuated Paralimbic and Reduced Mesolimbic D2/3-Impulsivity Associations in Parkinson's Disease

AJ Stark, AK Song, KJ Petersen, KR Hay… - Journal of …, 2023 - Soc Neuroscience
Impulsivity is a behavioral trait that is elevated in many neuropsychiatric disorders.
Parkinson's disease (PD) patients can exhibit a specific pattern of reward-seeking impulsive …

Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol

J Weafer, SM Gorka, M Dzemidzic… - …, 2021 - nature.com
Poor inhibitory control and heightened feelings of stimulation after alcohol are two well-
established risk factors for alcohol use disorder (AUD). Although these risk factors have …

[HTML][HTML] [18F] fallypride characterization of striatal and extrastriatal D2/3 receptors in Parkinson's disease

AJ Stark, CT Smith, KJ Petersen, P Trujillo… - NeuroImage: Clinical, 2018 - Elsevier
Parkinson's disease (PD) is characterized by widespread degeneration of monoaminergic
(especially dopaminergic) networks, manifesting with a number of both motor and non-motor …

Lack of consistent sex differences in d-amphetamine-induced dopamine release measured with [18F]fallypride PET

CT Smith, LC Dang, LL Burgess, SF Perkins… - …, 2019 - Springer
Rationale Sex differences in the dopaminergic response to psychostimulants could have
implications for drug abuse risk and other psychopathology involving the dopamine system …