Antibiotic resistance is a key medical concern, with antibiotic use likely being an important
cause. However, here we describe an alternative route to clinically relevant antibiotic …

Microbes often live in multispecies communities where interactions among community
members impact both the individual constituents and the surrounding environment. Here, we …

Background Lantibiotics are small microbial peptide antibiotics that are characterized by the
presence of the thioether amino acids lanthionine and methyllanthionine. Lantibiotics …

Staphylococcus aureus is the leading cause of nosocomial infections and a major cause of
community-acquired infections. Biofilm formation is a key virulence determinant in certain …

The Type VII protein secretion system, found in G ram‐positive bacteria, secretes small
proteins, containing a conserved W‐x‐G amino acid sequence motif, to the growth medium …

Peptidoglycan (PG) is the main component of bacterial cell walls and the target for many
antibiotics. PG biosynthesis is tightly coordinated with cell wall growth and turnover, and …

A central question to biology is how pathogenic bacteria initiate acute or chronic infections.
Here we describe a genetic program for cell-fate decision in the opportunistic human …

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) threatens
public health worldwide, and epidemiologic data suggest that the Panton-Valentine …

Background Three enterotoxins are implicated in diarrhoeal food poisoning due to Bacillus
cereus: Haemolysin BL (Hbl), Non-haemolytic enterotoxin (Nhe), and Cytotoxin K (CytK) …

The Hfq protein is reported to be an RNA chaperone, which is involved in the stress
response and the virulence of several pathogens. In E. coli, Hfq can mediate the interaction …