GABAergic signaling provides inhibitory stabilization and spatiotemporally coordinates the
firing of recurrently connected excitatory neurons in mature cortical circuits. Inhibition thus …

Calcium imaging is commonly used to visualize neural activity in vivo. In particular,
mesoscale calcium imaging provides large fields of view, allowing for the simultaneous …

Spontaneous activity during the early postnatal period is thought to be crucial for the
establishment of mature neural circuits. It remains unclear if the peripheral structure of the …

Individual neurons in sensory cortices exhibit specific receptive fields based on their
dendritic patterns. These dendritic morphologies are established and refined during the …

During early development, neurons in the brain often form excess synaptic connections.
Later, they strengthen some connections while eliminating others to build functional …

Spontaneous activity generated before the onset of sensory transduction has a key role in
wiring developing sensory circuits. From axonal targeting, to synapse formation and …

Neuronal activity, including sensory-evoked and spontaneous firing, regulates the
expression of a subset of genes known as activity-dependent genes. A key issue in this …

For neural circuit construction in the brain, coarse neuronal connections are assembled
prenatally following genetic programs, being reorganized postnatally by activity-dependent …

Brain development is highly dynamic and asynchronous, marked by the sequential
maturation of functional circuits across the brain. The timing and mechanisms driving circuit …

Animals must maintain their balance to navigate in their environment effectively. As animals
mature, their ability to correct their posture improves. Postural reflexes are driven by a …