[HTML][HTML] Data management in biobanking: strategies, challenges, and future directions

R Alkhatib, KI Gaede - BioTech, 2024 - mdpi.com
Biobanking plays a pivotal role in biomedical research by providing standardized
processing, precise storing, and management of biological sample collections along with the …

Repurposing therapeutic drugs complexed to vanadium in cancer

AL De Sousa-Coelho, G Fraqueza, M Aureliano - Pharmaceuticals, 2023 - mdpi.com
Repurposing drugs by uncovering new indications for approved drugs accelerates the
process of establishing new treatments and reduces the high costs of drug discovery and …

Network-based drug repurposing identifies small molecule drugs as immune checkpoint inhibitors for endometrial cancer

F Ahmed, A Samantasinghar, W Ali, KH Choi - Molecular Diversity, 2024 - Springer
Endometrial cancer (EC) is the 6th most common cancer in women around the world. Alone
in the United States (US), 66,200 new cases and 13,030 deaths are expected to occur in …

[HTML][HTML] Network-based drug repurposing for HPV-associated cervical cancer

F Ahmed, YJ Yang, A Samantasinghar, YW Kim… - Computational and …, 2023 - Elsevier
In women, cervical cancer (CC) is the fourth most common cancer around the world with
average cases of 604,000 and 342,000 deaths per year. Approximately 50% of high-grade …

Standardizing digital biobanks: integrating imaging, genomic, and clinical data for precision medicine

V Brancato, G Esposito, L Coppola, C Cavaliere… - Journal of Translational …, 2024 - Springer
Advancements in data acquisition and computational methods are generating a large
amount of heterogeneous biomedical data from diagnostic domains such as clinical …

A robust clustering strategy for stratification unveils unique patient subgroups in acutely decompensated cirrhosis

S Palomino-Echeverria, E Huergo… - Journal of Translational …, 2024 - Springer
Background Patient heterogeneity poses significant challenges for managing individuals
and designing clinical trials, especially in complex diseases. Existing classifications rely on …

Integrated ML-Based Strategy Identifies Drug Repurposing for Idiopathic Pulmonary Fibrosis

F Ahmed, A Samantasinghar, MA Bae, KH Choi - ACS omega, 2024 - ACS Publications
Idiopathic pulmonary fibrosis (IPF) affects an estimated global population of around 3 million
individuals. IPF is a medical condition with an unknown cause characterized by the …

Brain tumor detection with integrating traditional and computational intelligence approaches across diverse imaging modalities-Challenges and future directions

A Batool, YC Byun - Computers in Biology and Medicine, 2024 - Elsevier
Brain tumor segmentation and classification play a crucial role in the diagnosis and
treatment planning of brain tumors. Accurate and efficient methods for identifying tumor …

Repurposing metabolic regulators: Antidiabetic drugs as anticancer agents

Y Dhas, N Biswas, D MR, LD Jones, S Ashili - Molecular Biomedicine, 2024 - Springer
Drug repurposing in cancer taps into the capabilities of existing drugs, initially designed for
other ailments, as potential cancer treatments. It offers several advantages over traditional …

Integrating transcriptomic and structural insights: revealing drug repurposing opportunities for sporadic ALS

N Sunildutt, F Ahmed, AR Chethikkattuveli Salih… - ACS …, 2024 - ACS Publications
Amyotrophic lateral sclerosis (ALS) is a progressive and devastating neurodegenerative
disorder characterized by the loss of upper and lower motor neurons, resulting in debilitating …