The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the
gastrointestinal tract. This commensal microbiota can contribute to the regulation of host …

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily
affects joints. The several mechanisms involved in the development of the disease are not …

Stromal cells are a subject of rapidly growing immunological interest based on their ability to
influence virtually all aspects of innate and adaptive immunity. Present in every bodily tissue …

Stromal cells like synovial fibroblasts gained great interest over the years, since it has
become clear that they strongly influence their environment and neighbouring cells. The …

Fibroblasts in secondary lymphoid organs, or fibroblastic reticular cells (FRC), are gate-
keepers of immune responses. Here, we frame how these cells regulate immune responses …

Inflammation is a characteristic symptom of the occurrence and development of many
diseases, which is mainly characterized by the infiltration of inflammatory cells such as …

Immunometabolism has been an emerging hotspot in the fields of tumors, obesity, and
atherosclerosis in recent decades, yet few studies have investigated its connection with …

Objectives We investigated the reciprocal relationship linking fibroblast-like synoviocytes
(FLS) and T lymphocytes in the inflamed RA synovium and subsequently targeted cellular …

Objectives Increasing evidence suggests that inflammatory mechanisms play a key role in
chronic tendon disease. After observing T cell signatures in human tendinopathy, we …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by
neovascularization, immune cell infiltration, and synovial hyperplasia, which leads to …