Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y Xia - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

Adaptive immune receptor repertoire analysis

V Mhanna, H Bashour, K Lê Quý, P Barennes… - Nature Reviews …, 2024 - nature.com
B cell and T cell receptor repertoires compose the adaptive immune receptor repertoire
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …

Meta-analysis of the Parkinson's disease gut microbiome suggests alterations linked to intestinal inflammation

S Romano, GM Savva, JR Bedarf, IG Charles… - npj Parkinson's …, 2021 - nature.com
The gut microbiota is emerging as an important modulator of neurodegenerative diseases,
and accumulating evidence has linked gut microbes to Parkinson's disease (PD) …

[HTML][HTML] The lung microbiome regulates brain autoimmunity

L Hosang, RC Canals, FJ van der Flier, J Hollensteiner… - Nature, 2022 - nature.com
Lung infections and smoking are risk factors for multiple sclerosis, a T-cell-mediated
autoimmune disease of the central nervous system. In addition, the lung serves as a niche …

Ecological memory of recurrent drought modifies soil processes via changes in soil microbial community

A Canarini, H Schmidt, L Fuchslueger, V Martin… - Nature …, 2021 - nature.com
Climate change is altering the frequency and severity of drought events. Recent evidence
indicates that drought may produce legacy effects on soil microbial communities. However, it …

Tree islands enhance biodiversity and functioning in oil palm landscapes

DC Zemp, N Guerrero-Ramirez, F Brambach, K Darras… - Nature, 2023 - nature.com
Abstract In the United Nations Decade on Ecosystem Restoration, large knowledge gaps
persist on how to increase biodiversity and ecosystem functioning in cash crop-dominated …

Enhancing diversity analysis by repeatedly rarefying next generation sequencing data describing microbial communities

ES Cameron, PJ Schmidt, BJM Tremblay, MB Emelko… - Scientific reports, 2021 - nature.com
Amplicon sequencing has revolutionized our ability to study DNA collected from
environmental samples by providing a rapid and sensitive technique for microbial …

A comprehensive evaluation of microbial differential abundance analysis methods: current status and potential solutions

L Yang, J Chen - Microbiome, 2022 - Springer
Background Differential abundance analysis (DAA) is one central statistical task in
microbiome data analysis. A robust and powerful DAA tool can help identify highly confident …

Unraveling negative biotic interactions determining soil microbial community assembly and functioning

S Romdhane, A Spor, J Aubert, D Bru… - The ISME …, 2022 - academic.oup.com
Microbial communities play important roles in all ecosystems and yet a comprehensive
understanding of the ecological processes governing the assembly of these communities is …

Predicting measures of soil health using the microbiome and supervised machine learning

RC Wilhelm, HM van Es, DH Buckley - Soil Biology and Biochemistry, 2022 - Elsevier
Soil health encompasses a range of biological, chemical, and physical soil properties that
sustain the commercial and ecological value of agroecosystems. Monitoring soil health …