▪ Abstract Multistep chemical reactions are increasingly seen as important in a growing
number of complex biotransformations. Covalently attached prosthetic groups or swinging …

Microarrays fabricated with oligonucleotides longer than 40 bp have been introduced for
monitoring whole genome expression but have not been evaluated with environmental …

Malaria transmission-blocking vaccines (TBVs) reduce disease transmission by breaking the
continuous cycle of infection between the human host and the mosquito vector. Domain 1 …

Electron cryo‐microscopy of 'single particles' is a powerful method to determine the three‐
dimensional (3D) architectures of complex cellular assemblies. The pyruvate …

Encapsulation of active compounds in Pickering emulsions using bioderived protein-based
stabilizers holds potential for the development of novel formulations in the fields of foods and …

Vaccination has saved billions of human lives and has considerably reduced the economic
burden associated with pandemic and endemic infectious diseases. Notwithstanding major …

The pyruvate dehydrogenase multienzyme complexes are among the largest multifunctional
catalytic machines in cells, catalyzing the production of acetyl CoA from pyruvate. We have …

The high yields required for the economical production of chemicals and fuels using
microbes can be difficult to achieve due to the complexities of cellular metabolism. An …

The acyltransferase components (E2) from the family of 2-oxo acid dehydrogenase
multienzyme complexes form large protein scaffolds, to which multiple copies of peripheral …

Self‐assembling biological complexes such as viral capsids have been manipulated to
function in innovative nanotechnology applications. The E2 component of pyruvate …