The foundations of geometric morphometrics were worked out about 30 years ago and have
continually been refined and extended. What has remained as a central thrust and source of …

Phenotypic variation across mammals is extensive and reflects their ecological
diversification into a remarkable range of habitats on every continent and in every ocean …

Combined methylmalonic acidemia and homocystinuria (cblC) is the most common inborn
error of intracellular cobalamin metabolism and due to mutations in Methylmalonic Aciduria …

Hypochondroplasia (HCH) is a mild dwarfism caused by missense mutations in fibroblast
growth factor receptor 3 (FGFR3), with the majority of cases resulting from a heterozygous p …

Simple Summary Landmarks are commonly used to investigate how objects vary in form.
However, many objects present few identifiable landmarks. To remedy this, several …

ABSTRACT Down syndrome (DS), trisomy 21, results in many complex phenotypes
including cognitive deficits, heart defects and craniofacial alterations. Phenotypes arise from …

Modern microscopy technologies allow imaging biological objects in 3D over a wide range
of spatial and temporal scales, opening the way for a quantitative assessment of …

Adaptive avian radiations associated with the diversification of bird beaks into a multitude of
forms enabling different functions are exemplified by Darwin's finches and Hawaiian …

Complex morphological traits are the product of many genes with transient or lasting
developmental effects that interact in anatomical context. Mouse models are a key resource …

We present a novel method for the morphometric analysis of series of 3D shapes, and
demonstrate its relevance for the detection and quantification of two craniofacial anomalies …