The hitting set problem asks for a collection of sets over a universe U to find a minimum
subset of U that intersects each of the given sets. It is NP-hard and equivalent to the problem …

This book presents an experimental and computational account of the applications of
biopolymers in the field of medicine. Biopolymers are macromolecules produced by living …

Abstract The Systems Biology field presents several complex combinatorial problems that
can be in part reduced to an instance of the Hitting Set Problem (HSP), which is NP-Hard …

We present a hybrid exact algorithm for the Minimal Hitting Set (MHS) Enumeration Problem
for highly heterogeneous CPU‐GPU‐MIC platforms. With several techniques that permit an …

A model basically represents a system or an object under study, or may be an idea which
might represent the system. Simulation actually represents the operation of the model which …

Parallel and high performance computing is continuously gaining attention in the last years
as a means to accelerate several kind of computationally expensive applications. This …

Gene regulatory networks (GRN) inference is an important bioinformatics problem, with
many applications in system biology, in which the gene interactions need to be deduced …