Mechanisms of clathrin-mediated endocytosis

M Kaksonen, A Roux - Nature reviews Molecular cell biology, 2018 - nature.com
Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide
range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis …

To degrade or not to degrade: mechanisms and significance of endocytic recycling

PJ Cullen, F Steinberg - Nature reviews Molecular cell biology, 2018 - nature.com
Newly endocytosed integral cell surface proteins are typically either directed for degradation
or subjected to recycling back to the plasma membrane. The sorting of integral cell surface …

Visualizing intracellular organelle and cytoskeletal interactions at nanoscale resolution on millisecond timescales

Y Guo, D Li, S Zhang, Y Yang, JJ Liu, X Wang, C Liu… - Cell, 2018 - cell.com
In eukaryotic cells, organelles and the cytoskeleton undergo highly dynamic yet organized
interactions capable of orchestrating complex cellular functions. Visualizing these …

Peptide‐based coacervate‐core vesicles with semipermeable membranes

M Abbas, JO Law, SN Grellscheid… - Advanced …, 2022 - Wiley Online Library
Coacervates droplets have long been considered as potential protocells to mimic living
cells. However, these droplets lack a membrane and are prone to coalescence, limiting their …

An ESCRT-III polymerization sequence drives membrane deformation and fission

AK Pfitzner, V Mercier, X Jiang, JM von Filseck, B Baum… - Cell, 2020 - cell.com
The endosomal sorting complex required for transport-III (ESCRT-III) catalyzes membrane
fission from within membrane necks, a process that is essential for many cellular functions …

The 2018 biomembrane curvature and remodeling roadmap

P Bassereau, R Jin, T Baumgart… - Journal of physics D …, 2018 - iopscience.iop.org
The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

Endocytosis in the context-dependent regulation of individual and collective cell properties

S Sigismund, L Lanzetti, G Scita… - Nature Reviews Molecular …, 2021 - nature.com
Endocytosis allows cells to transport particles and molecules across the plasma membrane.
In addition, it is involved in the termination of signalling through receptor downmodulation …

Molecular mechanism of fast endophilin-mediated endocytosis

A Casamento, E Boucrot - Biochemical Journal, 2020 - portlandpress.com
Endocytosis mediates the cellular uptake of micronutrients and cell surface proteins. Clathrin-
mediated endocytosis (CME) is the housekeeping pathway in resting cells but additional …

Probing force in living cells with optical tweezers: from single-molecule mechanics to cell mechanotransduction

C Arbore, L Perego, M Sergides, M Capitanio - Biophysical reviews, 2019 - Springer
The invention of optical tweezers more than three decades ago has opened new avenues in
the study of the mechanical properties of biological molecules and cells. Quantitative force …

The hallmarks of living systems: towards creating artificial cells

NA Yewdall, AF Mason, JCM Van Hest - Interface Focus, 2018 - royalsocietypublishing.org
Despite the astonishing diversity and complexity of living systems, they all share five
common hallmarks: compartmentalization, growth and division, information processing …