This article reviews synthetic transformations involving cleavage of a carbon–carbon bond of
a four-membered ring, with a particular focus on the examples reported during the period …

Conspectus Bridged and fused rings are commonly found in biologically important
molecules. Current tactics to construct these ring systems are primarily based on stepwise …

The divergent catalytic reactions based on C–C activation of benzocyclobutenones have
been discovered, consisting of a highly enantioselective dearomatic “Cut & Sew” …

Herein, we describe the development of a deconstructive strategy for the first asymmetric
synthesis of (−)‐thebainone A, capitalizing on an enantioselective C− C bond activation and …

Herein, we describe the first total synthesis of sesquiterpene penicibilaenes A and B through
a “C–C/C–H” approach. In the “C–C” stage, the Rh-catalyzed “cut-and-sew” transformation …

Here, we describe a transition-metal-free condition that realized the intramolecular
acylfluorination of unactivated olefins. It was designed to access seven-membered-ring …

To the best of our knowledge, bridgehead carbon benzofused-bridged ring systems have
previously not been accessible to the synthetic community. Here, we describe a formal type …

Catalytic asymmetric transformations involving carbon‐carbon bond cleavages open
intriguing strategies for the synthesis of chiral complex molecules. The transient …

A novel catalytic asymmetric dienylation of para-quinone methides with allenoates has been
developed. Under mild conditions catalyzed by (R)-SITCP, various dienylated …

Herein, we report a novel strategy toward galanthamine and lycoramine. The concise
synthesis was enabled by a Rh-catalyzed gram-scale C–C activation for the tetracyclic …