Women that present to the clinic with established breast cancer metastases have limited
treatment options. Yet, the majority of preclinical studies are actually not directed at …

Vasculogenic mimicry (VM) describes the formation of pseudo blood vessels constructed of
tumor cells that have acquired endothelial-like properties. VM channels endow the tumor …

Asparagine, an important amino acid in mammals, is produced in several organs and is
widely used for the production of other nutrients such as glucose, proteins, lipids, and …

Background The optimal first-line immune checkpoint inhibitor (ICI) treatment strategy for
metastatic or early triple-negative breast cancer (TNBC) has not yet been determined as a …

The Imaging and Molecular Annotation of Xenografts and Tumors Cancer Grand Challenges
team was set up with the objective of developing the “next generation” of pathology and …