The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat
bacterial infections. The development of novel therapeutic agents is crucial in avoiding a …

There has been a resurgence in the clinical use of polymyxin antibiotics such as colistin due
to the limited treatment options for infections caused by carbapenem-resistant …

Introduction Infections caused by drug-resistant Klebsiella pneumoniae are now a serious
problem for public health, associated with high morbidity and mortality due to limited …

Colistin is a last resort antibiotic for the treatment of carbapenemase producing Klebsiella
pneumoniae. The disruption of the mgrB gene by insertion sequences (ISs) is a mechanism …

Tea tree oil (TTO) is an essential plant oil with diverse antibacterial and antioxidant
properties; however, whether the role played by TTO in low fish meal (LF) diets induced the …

Drug-resistant Enterobacterales infections are a great health concern due to the lack of
effective treatments. Consequently, finding novel antimicrobials or combining therapies …

Infectious diseases account for nine percent of annual human deaths, and the widespread
emergence of antimicrobial resistances threatens to significantly increase this number in the …

Background Colistin is used as a last resort for managing infections caused by multidrug-
resistant bacteria. However, the high emergence of colistin-resistant strains has restricted …

Innate immune stimulants, especially toll-like receptor (TLR) ligands and agonists, are the
main players in the initiation of innate immunity and have been widely studied as …

Colistin is a last resort antibiotic medication for the treatment of infections caused by
carbapenem-resistant Klebsiella pneumoniae. In recent years, various mechanisms have …