Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …

Ellagic acid (EA) is a dietary polyphenol present in various fruits, vegetables, herbs, and
nuts. It exists either independently or as part of complex structures, such as ellagitannins …

Abstract Nose-to-brain (N-to-B) delivery offers to protein and peptide drugs the possibility to
reach the brain in a non-invasive way. This article is a comprehensive review of the state-of …

Overnutrition and modern diets containing high proportions of saturated fat are among the
major factors contributing to a low-grade state of inflammation, hyperglycemia and …

Alzheimer's disease (AD) is a global concern and has become a major public health event
affecting human health. Insulin is a metabolic hormone secreted mainly by the peripheral …

Alzheimer's disease (AD) is prevalent in old age people and is one of the most common
brain diseases. Brain insulin resistance, neuroinflammation, oxidative stress, and …

The regulation of insulin on depression and depression‐like behaviour has been widely
reported. Insulin and activation of its receptor can promote learning and memory, affect the …

Recent evidence suggests that Alzheimer's disease (AD) is closely linked with insulin
resistance, as seen in type 2 diabetes mellitus (T2DM). Insulin signaling is impaired in AD …

Dulaglutide, a novel long-acting glucagon-like peptide 1 (GLP-1) receptor agonist, is an
incretin mimetic approved for type 2 diabetes mellitus (T2DM) treatment. Alzheimer's …

Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …