Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

Cardiovascular disease (CVD) is a health problem worldwide, and elevated cholesterol
levels are a key risk factor for the disease. Dysbiotic gut microbiota has been shown to be …

The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …

Human gut microbiota produce a variety of molecules, some of which enter the bloodstream
and impact health. Conversely, dietary or pharmacological compounds may affect the …

Evidence from human cohorts indicates that chronic insomnia is associated with higher risk
of cardiometabolic diseases (CMD), yet whether gut microbiota plays a role is unclear. Here …

Importance Metabolomics reflect the net effect of genetic and environmental influences and
thus provide a comprehensive approach to evaluating the pathogenesis of complex …

Increasing evidence suggests that gut dysbiosis plays vital roles in a variety of gut–brain
disorders, such as Alzheimer's disease (AD). However, alterations of the gut microbiota as …

CD36, located on the cell membrane, transports fatty acids in response to dietary fat. It is a
critical fatty acid sensor and regulator of lipid metabolism. The interaction between CD36 …

Short-chain fatty acids (SCFAs), as products of intestinal bacterial metabolism, are
particularly relevant in the diagnosis of intestinal dysbiosis. The most common studies of …

Studies of the human microbiome share both technical and conceptual similarities with
genome-wide association studies and genetic epidemiology. However, the microbiome has …