Repetitive DNA motifs are abundant in the genomes of various species and have the
capacity to adopt non-canonical (ie, non-B) DNA structures. Several non-B DNA structures …

Human centromeres have been extensively studied over the past two decades.
Consequently, more is known of centromere structure and organization in humans than in …

Cosmid clones containing human DNA inserts have been mapped on chromosome 11 by
fluorescence in situ hybridization under conditions that suppress signal from repetitive DNA …

Two de novo insertions of truncated L1 elements into the factor VIII gene on the X
chromosome have been identified that produced hemophilia A. A full-length L1 element that …

Fluorescence in situ hybridization to metaphase chromosomes or chromatin fibers in
interphase nuclei is a powerful technique in mapping genes and DNA segments to specific …

Neuronal nitric oxide (NO) synthase, localized to human chromosome 12, uniquely
participates in diverse biologic processes; neurotransmission, the regulation of body fluid …

The dinucleotide repetitive sequence,(GT) n, is highly interspersed in eukaryotic genomes
and may have functional roles in genetic recombination or the modulation of transcriptional …

Current efforts to map the human genome are focused on individual chromosomes or
smaller regions and frequently rely on the use of somatic cell hybrids. We report the …

Disperskm of repetitive sequence elements is a source of genetic variability that contributes
to genome evolution. Alu elements, the most common dispersed repeats in the human …

A complete physical map of the 11~ 13 region containing the Wilms' tumor locus has been
developed and used to localize a candidate Wilms' tumor gene. Our strategy to construct the …