The pathogenesis of Rift Valley fever

T Ikegami, S Makino - Viruses, 2011 - mdpi.com
Rift Valley fever (RVF) is an emerging zoonotic disease distributed in sub-Saharan African
countries and the Arabian Peninsula. The disease is caused by the Rift Valley fever virus …

Molecular biology and genetic diversity of Rift Valley fever virus

T Ikegami - Antiviral research, 2012 - Elsevier
Rift Valley fever virus (RVFV), a member of the family Bunyaviridae, genus Phlebovirus, is
the causative agent of Rift Valley fever (RVF), a mosquito-borne disease of ruminant animals …

Pathogenesis of emerging severe fever with thrombocytopenia syndrome virus in C57/BL6 mouse model

C Jin, M Liang, J Ning, W Gu, H Jiang… - Proceedings of the …, 2012 - National Acad Sciences
The discovery of an emerging viral disease, severe fever with thrombocytopenia syndrome
(SFTS), caused by SFTS virus (SFTSV), has prompted the need to understand pathogenesis …

IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus

R Mudhasani, JP Tran, C Retterer… - Journal of …, 2013 - Am Soc Microbiol
We show that interferon-induced transmembrane protein 1 (IFITM-1), IFITM-2, and IFITM-3
exhibit a broad spectrum of antiviral activity against several members of the Bunyaviridae …

Rift valley fever: recent insights into pathogenesis and prevention

H Boshra, G Lorenzo, N Busquets, A Brun - Journal of virology, 2011 - Am Soc Microbiol
Rift Valley fever virus (RVFV) is a zoonotic pathogen that primarily affects ruminants but can
also be lethal in humans. A negative-stranded RNA virus of the family Bunyaviridae, this …

Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control

S Wang, W Li, Z Wang, W Yang, E Li, X Xia… - … and Targeted Therapy, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …

Rift Valley fever virus MP-12 vaccine is fully attenuated by a combination of partial attenuations in the S, M, and L segments

T Ikegami, TE Hill, JK Smith, L Zhang… - Journal of …, 2015 - Am Soc Microbiol
Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and
characterized by a high rate of abortion in ruminants and hemorrhagic fever, encephalitis, or …

Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase

R Mudhasani, JP Tran, C Retterer, KP Kota… - PLoS …, 2016 - journals.plos.org
Activated protein kinase R (PKR) plays a vital role in antiviral defense primarily by inhibiting
protein synthesis and augmenting interferon responses. Many viral proteins have adopted …

Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated …

F Alem, AA Olanrewaju, S Omole, HE Hobbs, N Ahsan… - Cell & Bioscience, 2021 - Springer
Background Although multiple studies have demonstrated a role for exosomes during virus
infections, our understanding of the mechanisms by which exosome exchange regulates …

Molecular xenomonitoring using mosquitoes to map lymphatic filariasis after mass drug administration in American Samoa

MA Schmaedick, AL Koppel, N Pilotte… - PLoS neglected …, 2014 - journals.plos.org
Background Mass drug administration (MDA) programs have dramatically reduced
lymphatic filariasis (LF) incidence in many areas around the globe, including American …