[HTML][HTML] Vitamin D and chronic diseases

H Wang, W Chen, D Li, X Yin, X Zhang, N Olsen… - Aging and …, 2017 - ncbi.nlm.nih.gov
Vitamin D is one of the essential nutrients to sustain the human health. As a member of the
steroid hormone family, it has a classic role in regulating metabolism of calcium and a non …

New perspectives on the vitamin D binding protein

RF Chun - Cell biochemistry and function, 2012 - Wiley Online Library
The serum vitamin D binding protein (DBP), also known as GC‐globulin, is a multifunctional
protein known for its role in the transport of vitamin D metabolites. DBP also binds fatty acids …

Common variants of the vitamin D binding protein gene and adverse health outcomes

S Malik, L Fu, DJ Juras, M Karmali… - Critical reviews in …, 2013 - Taylor & Francis
The vitamin D binding protein (DBP) is the major plasma carrier for vitamin D and its
metabolites, but it is also an actin scavenger, and is the precursor to the immunomodulatory …

Small cell lung cancer: Recruitment of macrophages by circulating tumor cells

G Hamilton, B Rath, L Klameth, MJ Hochmair - Oncoimmunology, 2016 - Taylor & Francis
Tumor-associated macrophages (TAMs) play an important role in tumor progression,
suppression of antitumor immunity and dissemination. Blood monocytes infiltrate the tumor …

Impact of circulating vitamin D binding protein levels on the association between 25-hydroxyvitamin D and pancreatic cancer risk: a nested case–control study

SJ Weinstein, RZ Stolzenberg-Solomon, W Kopp… - Cancer research, 2012 - AACR
High concentrations of circulating 25-hydroxyvitamin D [25 (OH) D] have been associated
with elevated pancreatic cancer risk. As this is contrary to an expected inverse association …

Serum 25‐hydroxyvitamin D, vitamin D binding protein and risk of colorectal cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial

SJ Weinstein, MP Purdue… - … journal of cancer, 2015 - Wiley Online Library
The potential role of vitamin D in cancer prevention has generated substantial interest, and
laboratory experiments indicate several anti‐cancer properties for vitamin D compounds …

High glucose and insulin enhance uPA expression, ROS formation and invasiveness in breast cancer-derived cells

LA Flores-López, MG Martínez-Hernández… - Cellular Oncology, 2016 - Springer
Background Accumulating evidence indicates that type 2 diabetes is associated with an
increased risk to develop breast cancer. This risk has been attributed to hyperglycemia …

The molecular aspects of functional activity of macrophage-activating factor GcMAF

SS Kirikovich, EV Levites, AS Proskurina… - International Journal of …, 2023 - mdpi.com
Group-specific component macrophage-activating factor (GcMAF) is the vitamin D3-binding
protein (DBP) deglycosylated at Thr420. The protein is believed to exhibit a wide range of …

Molecular basis of prostate cancer and natural products as potential chemotherapeutic and chemopreventive agents

B Bai, Q Chen, R Jing, X He, H Wang, Y Ban… - Frontiers in …, 2021 - frontiersin.org
Prostate cancer is the second most common malignant cancer in males. It involves a
complex process driven by diverse molecular pathways that closely related to the survival …

Role of vitamin D in targeting cancer and cancer stem cell populations and its therapeutic implications

JB Marigoudar, D Sarkar, YM Yuguda, RF Abutayeh… - Medical Oncology, 2022 - Springer
Cancer is recognized globally as the second-most dominating and leading cause of
morbidities. Fighting the global health epidemic threat posed by cancer requires progress …