[HTML][HTML] Genetic variation of hepatitis B virus and its significance for pathogenesis

ZH Zhang, CC Wu, XW Chen, X Li, J Li… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) has a worldwide distribution and is endemic in many populations.
Due to its unique life cycle which requires an error-prone reverse transcriptase for …

Curcumin and photobiomodulation in chronic viral hepatitis and hepatocellular carcinoma

LM Ailioaie, G Litscher - International Journal of Molecular Sciences, 2020 - mdpi.com
Immune modulation is a very modern medical field for targeting viral infections. In the race to
develop the best immune modulator against viruses, curcumin, as a natural product, is …

[HTML][HTML] Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression

YM Choi, SY Lee, BJ Kim - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
The annual number of deaths caused by hepatitis B virus (HBV)-related disease, including
cirrhosis and hepatocellular carcinoma (HCC), is estimated as 887000. The reported …

High Prevalence of Hepatitis B Virus Drug Resistance Mutations to Lamivudine among People with HIV/HBV Coinfection in Rural and Peri-Urban Communities in …

BB Phinius, M Anderson, I Gobe, M Mokomane… - Viruses, 2024 - mdpi.com
(1) Background: We aimed to determine the prevalence of hepatitis B virus (HBV) resistance-
associated mutations (RAMs) in people with HBV and human immunodeficiency virus …

Characterization of full-length genomes of hepatitis B virus quasispecies in sera of patients at different phases of infection

ZT Yang, SY Huang, L Chen, F Liu… - Journal of Clinical …, 2015 - Am Soc Microbiol
Hepatitis B virus (HBV) infection results in different clinical presentation due to different
levels of immune response. Our study aimed to characterize HBV full-length genome …

HBV carrying drug-resistance mutations in chronically infected treatment-naive patients

MS Gomes-Gouvêa, AC Ferreira, R Teixeira… - Antiviral …, 2015 - journals.sagepub.com
Background Nucleoside/nucleotide analogue (NA) treatment causes selection pressure for
HBV strains carrying mutations conferring NA resistance. Drug-resistance mutations occur in …

Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy–Experienced Patients in Europe (CAPRE)

LE Hermans, V Svicher, SD Pas… - The Journal of …, 2016 - academic.oup.com
Background European guidelines recommend treatment of chronic hepatitis B virus infection
(CHB) with the nucleos (t) ide analogs (NAs) entecavir or tenofovir. However, many …

Occult hepatitis B virus infection in children born to HBsAg-positive mothers after neonatal passive-active immunoprophylaxis

H Foaud, S Maklad, F Mahmoud, H El-Karaksy - Infection, 2015 - Springer
Background Occult hepatitis B virus infection (OBI) is a well-recognized clinical entity
characterized by the detection of HBV DNA in serum and/or liver in the absence of …

Molecular epidemiology of hepatitis B virus mutants associated with vaccine escape, drug resistance and diagnosis failure

FA Di Lello, E Ridruejo, AP Martínez… - Journal of Viral …, 2019 - Wiley Online Library
The massive implementation of the vaccine and antiviral agents against hepatitis B virus
(HBV), targeting the envelope and viral polymerase genes, induces a selection pressure that …

Occult and active hepatitis B virus detection in donated blood in São Paulo, Brazil

AS Nishiya, JE Levi, C de Almeida‐Neto… - …, 2021 - Wiley Online Library
Background The present study determined the HBV antigen, antibody, and DNA status in
blood donations deemed to be HBV positive. Individuals with an occult HBV infection (OBI) …