Alzheimer's disease (AD), the most common form of dementia, is a striking example of the
connection between neurophysiological abnormalities and higher-order cognitive …

Abstract Alzheimer's disease (AD), as a neurodegenerative process caused by widespread
senile plaques and neurofibrillary tangles, is faced with an increasingly higher incidence as …

Brain connectivity studies have revealed that highly connected 'hub'regions are particularly
vulnerable to Alzheimer pathology: they show marked amyloid-β deposition at an early …

Despite the prevalence and impact of mild traumatic brain injury (mTBI), common clinical
assessment methods for mTBI have insufficient sensitivity and specificity. Moreover, few …

Higher general intelligence attenuates age-associated cognitive decline and the risk of
dementia. Thus, intelligence has been associated with cognitive reserve or resilience in …

Higher general cognitive ability (GCA) is associated with lower risk of neurodegenerative
disorders, but neural mechanisms are unknown. GCA could be associated with more cortical …

First-degree relatives of individuals with late-onset Alzheimer's disease (LOAD) are at
increased risk for developing dementia, yet the associations between family history of LOAD …

Introduction Previous studies have demonstrated that an overall high level of mental work
demands decreased dementia risk. In our study, we investigated whether this effect is driven …

Objective. This research aims to determine whether residence (rural vs. urban) at different
life stages (childhood, adulthood, and late life) is associated with increased risk of incident …

Growing evidence suggests the effect of educational attainment (EA) on Alzheimer's disease
(AD), but less is known about the shared genetic architecture between them. Here …