Chiral amino acids are extensively applied in the pharmaceutical, food, cosmetic,
agricultural, and feedstuff industries. The development of synthetic methodologies for …

The use of enzymes as catalysts for the preparation of novel compounds has received
steadily increasing attention over the past few years. High demands are placed on the …

Ammonia-lyases and aminomutases are mechanistically and structurally diverse enzymes
which catalyze the deamination and/or isomerization of amino acids in nature by cleaving or …

Rosmarinic acid (RA) is an ester of caffeic acid and 3, 4-dihydroxyphenyllactic acid which is
one of the most frequently occurring caffeic acid esters in the plant kingdom besides …

As one of the most economically significant Oleaceae family members, Jasminum sambac is
renowned for its distinct sweet, heady fragrance. Using Illumina reads, Nanopore long …

Ammonia lyases (AL) and aminomutases (AM) are emerging in green synthetic routes to
chiral amines and an AL is being explored as an enzyme therapeutic for treating …

Covering: 1966 to 2012 The biosynthesis of the anti-cancer drug taxol (paclitaxel) has
required the collaborative efforts of several research groups to tackle the synthesis and …

Deep mutational scanning (DMS) has recently emerged as a powerful method to study
protein sequence–function relationships but is not well-explored as a guide to enzyme …

Modification of the hydrophobic binding pocket of phenylalanine ammonia-lyase from
Petroselinum crispum (Pc PAL) enables increased activity and selectivity toward …

The enzyme family harboring the post-translationally formed 5-methylene-3, 5-dihydro-4 H-
imidazol-4-one (MIO) catalytic residue comprises both aromatic amino acid ammonia-lyases …