Angiogenesis and lymphangiogenesis often occur in response to tissue injury or in the
presence of pathology (eg, cancer), and it is these types of environments in which …

Osteal macrophages (OsteoMacs) are a special subtype of macrophage residing in bony
tissues. Interesting findings from basic research have pointed to their vast and substantial …

Macrophages are abundant in almost all tissues of all multicellular organisms, estimated to
total 10 10 cells in adult humans. Macrophage function is essential for health, as strikingly …

Macrophages are key players in many physiological scenarios including tissue
homeostasis. In response to injury, typically the balance between macrophage sub …

Many studies in the bone tissue engineering field have focused on the interactions between
materials and bone marrow stem cells. With the development of osteoimmunology, the …

Background Bone formation and remodeling are influenced by the inflammatory state of the
local microenvironment. In this regard, macrophages are postulated to play a crucial role in …

Multinucleated giant cells (MNGCs) are a special class of giant cell formed by the fusion of
monocytes/macrophages abundantly found in human tissues. While historically their role …

A key aspect of atherosclerosis is the maladaptive inflammatory response to lipoprotein
accumulation in the artery. The failure to decrease lipid accumulation, to clear apoptotic …

Significance: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus
causing coronavirus disease 2019 (COVID-19), affects every aspect of human life by …

The process of inflammation is orchestrated by macrophages, according to their state of
differentiation: thus, classically activated (M1) macrophages initiate the process by …