HPLC methods for the determination of simvastatin and atorvastatin

L Nováková, D Šatínský, P Solich - TrAC Trends in Analytical Chemistry, 2008 - Elsevier
We review high-performance liquid chromatography (HPLC) methods for the determination
of two major statins used in clinical treatment–simvastatin and atorvastatin–in various fields …

Recent advances in the impurity profiling of drugs

D Bartos, S Gorog - Current Pharmaceutical Analysis, 2008 - ingentaconnect.com
Drug impurity profiling, ie identification, structure elucidation and quantitative determination
of impurities and degradation products in bulk drug materials and pharmaceutical …

Optimisation and validation of a rapid and efficient microemulsion liquid chromatographic (MELC) method for the determination of paracetamol (acetaminophen) …

E McEvoy, S Donegan, J Power, K Altria - Journal of Pharmaceutical and …, 2007 - Elsevier
A rapid and efficient oil-in-water microemulsion liquid chromatographic method has been
optimised and validated for the analysis of paracetamol in a suppository formulation …

Desirability-based optimization and its sensitivity analysis for the perindopril and its impurities analysis in a microemulsion LC system

A Malenović, Y Dotsikas, M Mašković… - Microchemical …, 2011 - Elsevier
In the current paper the application of multiobjective optimization (MOOP) technique, via
Derringer's desirability function, to a microemulsion liquid chromatographic (MELC) method …

Comparison of UV and charged aerosol detection approach in pharmaceutical analysis of statins

L Nováková, SA Lopéz, D Solichová, D Šatínský… - Talanta, 2009 - Elsevier
CAD (charged aerosol detector) has recently become a new alternative detection system in
HPLC. This detection approach was applied in a new HPLC method for the determination of …

Pharmaceuticals and related drugs

RK Gilpin, CS Gilpin - Analytical chemistry, 2007 - ACS Publications
The current article surveys pharmaceutical analysis and related methodology that has
appeared in the literature since the last review in this series was published in Analytical …

Significance of stressor media on the stability of statins: a critical assessment

DS Lalchandani, L Chenkual, M Mariappayan… - Chemical Papers, 2022 - Springer
Statins are the most prescribed HMG CoA reductase inhibitors for the treatment of anti-
hyperlipidemia either alone or in combination with other pharmacotherapeutic agents …

Oil-in-water microemulsion liquid chromatography

E Peris-García, N Pankajkumar-Patel… - Separation & …, 2020 - Taylor & Francis
Oil-in-water microemulsions (O/W MEs) are obtained spontaneously by mixing two
immiscible liquids (water and oil) in the presence of a surfactant. A co-surfactant is also often …

Influence of structural and interfacial properties of microemulsion eluent on chromatographic separation of simvastatin and its impurities

M Anđelija, I Darko, M Mirjana, J Biljana… - … of chromatography A, 2006 - Elsevier
In order to calculate the structural and compositional characteristics of microemulsions, used
as eluents in the investigation of HPLC separation of simvastatin and its six impurities …

Simultaneous determination of enalapril and hydrochlorothiazide in pharmaceutical preparations using microemulsion liquid chromatography

MEA Hammouda, MA Abu El-Enin… - Journal of …, 2015 - academic.oup.com
A rapid high-performance liquid chromatography procedure for analytical quality control of
mixture containing enalapril maleate (ENM) and hydrochlorothiazide (HCT) in their …